Hs01803309_cn

• Gene Symbol: SERPINA5
• Assay Reference Genome Location: Chr.14:94592079 on build GRCh38
• Cytoband: 14q32.13

Target Gene Details

• Entrez Gene ID: 5104
• Gene Name: serpin family A member 5
• Gene Aliases: PAI-3, PAI3, PCI, PCI-B, PLANH3, PROCI
• Location: Chr.14:94581369-94593120 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERPINA5	NM_000624.5			NP_000615.3
	AK096131.1
	AK293192.1
	AK298279.1
	AL080185.1			CAB45766.1
	BC008915.2			AAH08915.1
	J02639.1			AAA35688.1
	S58545.1			AAB26244.2
	U35464.1			AAB60386.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv565626	Chr.14:94583971 - 94592873 on Build GRCh38	Loss	SERPINA5
nsv565625	Chr.14:94567019 - 94603850 on Build GRCh38	Loss	SERPINA4 SERPINA5
nsv470662	Chr.14:94296542 - 94798793 on Build GRCh38	Gain	SERPINA13P GSC SERPINA9 SERPINA11 SERPINA3 SERPINA4 SERPINA6 SERPINA2 SERPINA1 SERPINA12 SERPINA5
nsv565623	Chr.14:94393116 - 94635006 on Build GRCh38	Gain	SERPINA9 SERPINA11 SERPINA3 SERPINA4 SERPINA12 SERPINA5
nsv832865	Chr.14:94499457 - 94667894 on Build GRCh38	Gain	SERPINA13P SERPINA3 SERPINA4 SERPINA12 SERPINA5
esv3635384	Chr.14:94569665 - 94707857 on Build GRCh38	Gain	SERPINA13P SERPINA3 SERPINA4 SERPINA5

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

lipid transport
spermatogenesis
fusion of sperm to egg plasma membrane
blood coagulation
negative regulation of endopeptidase activity
negative regulation of hydrolase activity

Function(s)

retinoic acid binding
protease binding
serine-type endopeptidase inhibitor activity
protein binding
glycosaminoglycan binding
heparin binding
phosphatidylcholine binding
acrosin binding