Hs01815166_cn

• Gene Symbol: PNPO
• Assay Reference Genome Location: Chr.17:47946376 on build GRCh38
• Cytoband: 17q21.32

Target Gene Details

• Entrez Gene ID: 55163
• Gene Name: pyridoxamine 5'-phosphate oxidase
• Gene Aliases: HEL-S-302, PDXPO
• Location: Chr.17:47941523-47949308 on Build GRCh38
• Assay Gene Location: Overlaps Exon 6 - Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PNPO	NM_018129.3			NP_060599.1
	XM_005257500.3			XP_005257557.1
	XM_011524968.2			XP_011523270.1
	XM_017024813.1			XP_016880302.1
	AF468030.1			AAM76918.1
	AK001397.1			BAA91668.1
	AK223242.1			BAD96962.1
	AK303536.1
	AK303665.1
	AK303792.1
	BC006525.2			AAH06525.1
	FJ224333.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv1000014	Chr.17:47941862 - 47952091 on Build GRCh38	Deletion	PNPO PRR15L
nsv518892	Chr.17:47810585 - 47952066 on Build GRCh38	Loss	PNPO SP2 SCRN2 LOC102724532 PRR15L SP2-AS1 OSBPL7 SP6 MRPL10 LRRC46

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
pyridoxine biosynthetic process
vitamin B6 metabolic process
pyridoxal phosphate biosynthetic process
oxidation-reduction process
mitophagy in response to mitochondrial depolarization
xenophagy

Function(s)

pyridoxamine-phosphate oxidase activity
FMN binding