Hs01861670_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143992474 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1			NP_000828.1
	NM_001009184.1			NP_001009184.1
	AB097026.1			BAC77379.1
	AK127640.1
	AK294127.1
	BC041788.1			AAH41788.2
	BC084553.1			AAH84553.1
	U44954.1			AAB94292.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	PARP10 PLEC GRINA
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	BOP1 MAF1 DGAT1 CYC1 MIR6847 SCRT1 RECQL4 MFSD3 FOXH1 GPAA1 TONSL-AS1 LRRC14 MIR6849 MROH1 TMEM249 VPS28 ADCK5 MIR6848 MIR1234 WDR97 PLEC HSF1 SHARPIN HGH1 PPP1R16A SMPD5 MIR7112 TONSL SPATC1 EXOSC4 SLC52A2 MIR661 MIR6893 MIR939 PARP10 CPSF1 MIR6846 LOC101928902 GRINA CYHR1 KIFC2 FBXL6 GPT LOC101928953 SCX SLC39A4 OPLAH
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	BOP1 MAF1 DGAT1 CYC1 MIR6847 SCRT1 RECQL4 MFSD3 FOXH1 GPAA1 TONSL-AS1 LRRC14 MIR6849 MROH1 TMEM249 VPS28 ADCK5 MIR6848 MIR1234 WDR97 PLEC HSF1 SHARPIN HGH1 PPP1R16A SMPD5 MIR7112 TONSL SPATC1 EXOSC4 SLC52A2 MIR661 MIR6893 MIR939 PARP10 CPSF1 MIR6846 LOC101928902 GRINA CYHR1 KIFC2 FBXL6 GPT LOC101928953 SCX SLC39A4 OPLAH
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	WDR97 PLEC SHARPIN MAF1 SMPD5 CYC1 MIR6847 SPATC1 EXOSC4 GPAA1 PARP10 MIR6846 GRINA OPLAH
dgv12431n54	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	WDR97 PLEC SHARPIN HGH1 MAF1 SMPD5 EPPK1 CYC1 MIR6847 SPATC1 EXOSC4 MIR661 GPAA1 PARP10 MIR6846 MROH1 GRINA OPLAH
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	WDR97 PLEC SHARPIN MAF1 SMPD5 EPPK1 CYC1 MIR6847 SPATC1 EXOSC4 MIR661 GPAA1 PARP10 MIR6846 GRINA OPLAH
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	MIR937 SCRIB PLEC NRBP2 SMPD5 EPPK1 MIR6847 SPATC1 EXOSC4 MIR661 MIR6845 LOC642574 PARP10 MIR6846 GRINA PUF60 OPLAH
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	GPAA1 PARP10 PLEC MIR6846 SMPD5 GRINA CYC1 MIR6847 SPATC1 EXOSC4 MIR661 OPLAH
dgv12433n54	Chr.8:143902404 - 144120626 on Build GRCh38	Gain	WDR97 PLEC SHARPIN MAF1 SMPD5 CYC1 MIR6847 SPATC1 EXOSC4 MIR661 GPAA1 PARP10 MIR6846 GRINA OPLAH
nsv612906	Chr.8:143917935 - 144090784 on Build GRCh38	Loss	GPAA1 PARP10 PLEC MIR6846 SMPD5 GRINA MIR6847 SPATC1 EXOSC4 MIR661 OPLAH

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding