Hs01861670_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143992474 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1			NP_000828.1
	NM_001009184.1			NP_001009184.1
	AB097026.1			BAC77379.1
	AK127640.1
	AK294127.1
	BC041788.1			AAH41788.2
	BC084553.1			AAH84553.1
	U44954.1			AAB94292.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	PARP10 PLEC GRINA
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	MIR6846 VPS28 SHARPIN MROH1 MIR6847 LOC101928902 OPLAH MAF1 RECQL4 BOP1 SPATC1 MIR1234 KIFC2 MIR6893 TONSL TONSL-AS1 SCX MIR6849 PPP1R16A GPAA1 LOC101928953 DGAT1 MIR661 MIR7112 MFSD3 WDR97 SMPD5 ADCK5 SLC39A4 GRINA PARP10 CYHR1 HGH1 LRRC14 CPSF1 TMEM249 FOXH1 CYC1 PLEC GPT HSF1 EXOSC4 SLC52A2 SCRT1 FBXL6 MIR6848 MIR939
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	MIR6846 VPS28 SHARPIN MROH1 MIR6847 LOC101928902 OPLAH MAF1 RECQL4 BOP1 SPATC1 MIR1234 KIFC2 MIR6893 TONSL TONSL-AS1 SCX MIR6849 PPP1R16A GPAA1 LOC101928953 DGAT1 MIR661 MIR7112 MFSD3 WDR97 SMPD5 ADCK5 SLC39A4 GRINA PARP10 CYHR1 HGH1 LRRC14 CPSF1 TMEM249 FOXH1 CYC1 PLEC GPT HSF1 EXOSC4 SLC52A2 SCRT1 FBXL6 MIR6848 MIR939
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	MIR6846 SHARPIN MIR6847 WDR97 SMPD5 OPLAH MAF1 SPATC1 GRINA PARP10 CYC1 PLEC EXOSC4 GPAA1
dgv906n27	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	MIR6846 SHARPIN MIR661 MROH1 MIR6847 WDR97 SMPD5 OPLAH MAF1 SPATC1 GRINA PARP10 HGH1 EPPK1 CYC1 PLEC EXOSC4 GPAA1
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	MIR6846 SHARPIN MIR661 MIR6847 WDR97 SMPD5 OPLAH MAF1 SPATC1 GRINA PARP10 EPPK1 CYC1 PLEC EXOSC4 GPAA1
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	PUF60 MIR6846 MIR661 NRBP2 MIR6847 SMPD5 OPLAH MIR937 SPATC1 GRINA PARP10 EPPK1 MIR6845 PLEC SCRIB LOC642574 EXOSC4
dgv12432n54	Chr.8:143902404 - 144007080 on Build GRCh38	Loss	PARP10 MIR661 PLEC GRINA
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	PARP10 MIR6846 MIR661 CYC1 PLEC MIR6847 SMPD5 OPLAH EXOSC4 GPAA1 SPATC1 GRINA
nsv612907	Chr.8:143917935 - 144097007 on Build GRCh38	Gain+Loss	PARP10 MIR6846 MIR661 CYC1 PLEC MIR6847 SMPD5 OPLAH EXOSC4 GPAA1 SPATC1 GRINA

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding