Hs01874617_cn

• Gene Symbol: UBE2L6
• Assay Reference Genome Location: Chr.11:57552008 on build GRCh38
• Cytoband: 11q12.1

Target Gene Details

• Entrez Gene ID: 9246
• Gene Name: ubiquitin conjugating enzyme E2 L6
• Gene Aliases: RIG-B, UBCH8
• Location: Chr.11:57551655-57568330 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBE2L6	NM_004223.4	4	908	NP_004214.1
	NM_198183.2	4	1267	NP_937826.1
	AF061736.1	4	859	AAD17525.1
	AK093462.1	4	1221
	AK129621.1	4	779
	AK226165.1	4	962
	BC032491.1	4	908	AAH32491.1
	H17887.1	1	376

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832163	Chr.11:57531881 - 57713578 on Build GRCh38	Gain	SMTNL1 TMX2 SERPING1 TMX2-CTNND1 YPEL4 UBE2L6 MED19 MIR130A CLP1 ZDHHC5

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

cellular protein modification process
protein ubiquitination
modification-dependent protein catabolic process
translesion synthesis
ISG15-protein conjugation
negative regulation of type I interferon production
cellular protein metabolic process

Function(s)

ubiquitin-protein transferase activity
protein binding
ISG15 transferase activity
ubiquitin binding