Hs01881699_cn

• Gene Symbol: CREB3
• Assay Reference Genome Location: Chr.9:35732369 on build GRCh38
• Cytoband: 9p13.3

Target Gene Details

• Entrez Gene ID: 10488
• Gene Name: cAMP responsive element binding protein 3
• Gene Aliases: LUMAN, LZIP, sLZIP
• Location: Chr.9:35732320-35737008 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CREB3	NM_006368.4	1	50	NP_006359.3
	AF211848.1			AAG43528.1
	BG701230.1	1	55

Target Gene Details

• Entrez Gene ID: 7094
• Gene Name: talin 1
• Gene Aliases: ILWEQ, TLN
• Location: Chr.9:35697337-35732395 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TLN1	NM_006289.3			NP_006280.3
	AB028950.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv25437	Chr.9:35728113 - 35732419 on Build GRCh38	Loss	CREB3 TLN1

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
chemotaxis
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
viral process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of monocyte chemotaxis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
platelet degranulation
movement of cell or subcellular component
muscle contraction
cytoskeletal anchoring at plasma membrane
cell-cell junction assembly
cell-substrate junction assembly
cortical actin cytoskeleton organization
IRE1-mediated unfolded protein response
platelet aggregation

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
cAMP response element binding
integrin binding
structural constituent of cytoskeleton
vinculin binding
LIM domain binding
actin filament binding
cadherin binding involved in cell-cell adhesion