Hs01892235_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137175833 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps Intron 10 - Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	RNF224 RNF208 TMEM210 SLC34A3 LOC101930307 NDOR1 CYSRT1 ANAPC2 GRIN1 DPP7 TPRN TMEM203 MIR3621 LRRC26 UAP1L1 SSNA1 MAN1B1-AS1 MAN1B1
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	NELFB RNF224 RNF208 TOR4A SLC34A3 NDOR1 CYSRT1 ANAPC2 EXD3 STPG3 FAM166A TUBB4B TPRN TMEM203 SSNA1 NRARP C9orf173-AS1
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	RNF224 ABCA2 TOR4A LOC101930307 CYSRT1 ANAPC2 GRIN1 C9orf172 TMEM203 MIR3621 NRARP CLIC3 PNPLA7 MAMDC4 MAN1B1-AS1 NOXA1 MIR4479 PTGDS RNF208 NPDC1 C8G NDOR1 EXD3 LCNL1 MIR7114 LRRC26 FBXW5 C9orf142 NSMF PHPT1 EDF1 CCDC183-AS1 TMEM210 SLC34A3 SAPCD2 RABL6 ENTPD8 SSNA1 MAN1B1 CCDC183 TRAF2 NELFB LCN12 MIR4292 ENTPD2 C9orf139 PRR31 STPG3 FAM166A TUBB4B DPP7 FUT7 TPRN UAP1L1 C9orf173-AS1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	NELFB RNF224 RNF208 TOR4A TMEM210 SLC34A3 NDOR1 CYSRT1 ANAPC2 EXD3 STPG3 FAM166A GRIN1 TUBB4B TPRN TMEM203 MIR3621 LRRC26 SSNA1 NRARP C9orf173-AS1
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	NPDC1 TMEM210 LOC101930307 ENTPD2 C9orf139 SAPCD2 ANAPC2 GRIN1 DPP7 FUT7 MIR3621 LRRC26 UAP1L1 SSNA1 MAN1B1-AS1 MAN1B1
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	NELFB RNF224 RNF208 TOR4A TMEM210 SLC34A3 NDOR1 CYSRT1 ANAPC2 EXD3 STPG3 FAM166A GRIN1 TUBB4B TPRN ENTPD8 TMEM203 MIR3621 LRRC26 SSNA1 NRARP C9orf173-AS1 NOXA1
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	RNF224 ABCA2 TOR4A LOC101930307 CYSRT1 SNORA17B ANAPC2 LCN8 GRIN1 C9orf172 LINC01451 MIR126 TMEM203 MIR3621 NRARP CLIC3 MAMDC4 MAN1B1-AS1 MIR4479 PTGDS RNF208 NPDC1 C8G NDOR1 EXD3 LCNL1 LRRC26 FBXW5 C9orf142 PHPT1 MIR6722 FAM69B EDF1 CCDC183-AS1 LCN15 LCN10 TMEM210 SLC34A3 LOC100128593 SAPCD2 TMEM141 RABL6 SSNA1 AGPAT2 MAN1B1 CCDC183 HSPC324 TRAF2 NELFB EGFL7 LCN12 MIR4292 SNORA17A ENTPD2 C9orf139 LCN6 PRR31 STPG3 FAM166A TUBB4B DPP7 FUT7 TPRN UAP1L1 C9orf173-AS1 SNHG7

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity