Hs01907495_cn

• Gene Symbol: KLK8
• Assay Reference Genome Location: Chr.19:51000226 on build GRCh38
• Cytoband: 19q13.41

Target Gene Details

• Entrez Gene ID: 11202
• Gene Name: kallikrein related peptidase 8
• Gene Aliases: HNP, NP, NRPN, PRSS19, TADG14
• Location: Chr.19:50996008-51001702 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLK8	NM_001281431.1			NP_001268360.1
	NM_007196.3			NP_009127.1
	NM_144505.2			NP_653088.1
	NM_144506.2			NP_653089.1
	NM_144507.2			NP_653090.1
	NR_104008.1
	AA320217.1
	AA587273.1
	AB008390.2			BAA82665.1
	AB008927.1			BAA82666.1
	AB009849.1			BAA28673.1
	AF095742.1			AAD25979.1
	AY359036.1			AAQ89395.1
	BM845575.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3644662	Chr.19:50996542 - 51001686 on Build GRCh38	Loss	KLK8
nsv1058277	Chr.19:50985288 - 51006591 on Build GRCh38	Gain	KLK9 KLK8

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease, serine protease, protein modifying enzyme

Gene Ontology Categories:

Process(es)

proteolysis
memory
cell death
response to wounding
negative regulation of myelination
keratinocyte proliferation
negative regulation of axon regeneration
neuron projection morphogenesis
regulation of synapse organization
synapse organization

Function(s)

serine-type endopeptidase activity
protein binding