Hs01928784_cn

• Gene Symbol: ADORA2A
• Assay Reference Genome Location: Chr.22:24442363 on build GRCh38
• Cytoband: 22q11.23

Target Gene Details

• Entrez Gene ID: 135
• Gene Name: adenosine A2a receptor
• Gene Aliases: A2aR, ADORA2, RDC8
• Location: Chr.22:24423597-24442360 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A	NM_000675.5			NP_000666.2
	NM_001278497.1			NP_001265426.1
	NM_001278498.1			NP_001265427.1
	NM_001278499.1			NP_001265428.1
	NM_001278500.1			NP_001265429.1
	NR_103543.1
	NR_103544.1
	AK123058.1
	BC013780.1			AAH13780.1
	CA307692.1
	M97370.1			AAA58356.1

Target Gene Details

• Entrez Gene ID: 646023
• Gene Name: ADORA2A antisense RNA 1
• Gene Aliases: C22orf45
• Location: Chr.22:24429206-24495074 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A-AS1	NR_028483.2
	NR_028484.2
	DB449907.2

Target Gene Details

• Entrez Gene ID: 101730217
• Gene Name: SPECC1L-ADORA2A readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.22:24270817-24442360 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPECC1L-ADORA2A	NR_103546.1
	AB209022.1			BAD92259.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv8039n54	Chr.22:23323169 - 24601506 on Build GRCh38	Gain	CES5AP1 ZDHHC8P1 RGL4 PCAT14 SLC2A11 ZNF70 SPECC1L-ADORA2A POM121L9P MMP11 LOC388882 VPREB3 DDT ADORA2A-AS1 ADORA2A MIF-AS1 SPECC1L GSTT2B DDTL DERL3 SUSD2 UPB1 DRICH1 IGLL1 LOC107985559 CABIN1 GGT1 LRRC75B LOC107985555 GUSBP11 MIF GSTT2 SMARCB1 SNRPD3 LOC100652871 C22orf15 GUCD1 GSTTP1 GGT5 LOC101929374 CHCHD10
esv2724068	Chr.22:24288741 - 24669870 on Build GRCh38	Deletion	ADORA2A-AS1 ADORA2A SNRPD3 SPECC1L POM121L10P GGT1 GUCD1 LRRC75B UPB1 BCRP3 SPECC1L-ADORA2A
nsv1057819	Chr.22:24290518 - 24624081 on Build GRCh38	Gain	ADORA2A-AS1 ADORA2A SNRPD3 SPECC1L GGT1 GUCD1 LRRC75B UPB1 SPECC1L-ADORA2A
esv2724041	Chr.22:23315914 - 24669376 on Build GRCh38	Deletion	CES5AP1 ZDHHC8P1 RGL4 PCAT14 SLC2A11 ZNF70 SPECC1L-ADORA2A POM121L9P MMP11 LOC388882 VPREB3 DDT ADORA2A-AS1 ADORA2A MIF-AS1 SPECC1L GSTT2B DDTL DERL3 SUSD2 UPB1 DRICH1 IGLL1 LOC107985559 BCRP3 CABIN1 BCR POM121L10P GGT1 LRRC75B LOC107985555 GUSBP11 MIF GSTT2 SMARCB1 SNRPD3 LOC100652871 C22orf15 GUCD1 GSTTP1 GGT5 LOC101929374 CHCHD10
nsv526567	Chr.22:23348138 - 24600663 on Build GRCh38	Gain	CES5AP1 ZDHHC8P1 RGL4 PCAT14 SLC2A11 ZNF70 SPECC1L-ADORA2A POM121L9P MMP11 LOC388882 VPREB3 DDT ADORA2A-AS1 ADORA2A MIF-AS1 SPECC1L GSTT2B DDTL DERL3 SUSD2 UPB1 DRICH1 IGLL1 LOC107985559 CABIN1 GGT1 LRRC75B LOC107985555 GUSBP11 MIF GSTT2 SMARCB1 SNRPD3 LOC100652871 C22orf15 GUCD1 GSTTP1 GGT5 LOC101929374 CHCHD10
nsv1055830	Chr.22:24005071 - 24643213 on Build GRCh38	Gain	GGT1 LRRC75B SPECC1L-ADORA2A POM121L9P ADORA2A-AS1 ADORA2A SNRPD3 SPECC1L GUCD1 SUSD2 UPB1 GSTTP1 BCRP3 GGT5 CABIN1
esv3893463	Chr.22:24009046 - 24601506 on Build GRCh38	Gain	GGT1 LRRC75B SPECC1L-ADORA2A POM121L9P ADORA2A-AS1 ADORA2A SNRPD3 SPECC1L GUCD1 SUSD2 UPB1 GGT5 CABIN1
dgv4528n100	Chr.22:23322244 - 24682765 on Build GRCh38	Gain	CES5AP1 ZDHHC8P1 RGL4 PCAT14 SLC2A11 ZNF70 SPECC1L-ADORA2A POM121L9P MMP11 LOC388882 VPREB3 DDT ADORA2A-AS1 ADORA2A MIF-AS1 SPECC1L GSTT2B DDTL DERL3 SUSD2 UPB1 DRICH1 IGLL1 LOC107985559 BCRP3 CABIN1 POM121L10P GGT1 LRRC75B LOC107985555 GUSBP11 MIF GSTT2 SMARCB1 SNRPD3 LOC100652871 C22orf15 GUCD1 GSTTP1 GGT5 LOC101929374 CHCHD10
nsv588744	Chr.22:24285587 - 24617379 on Build GRCh38	Gain	ADORA2A-AS1 ADORA2A SNRPD3 SPECC1L GGT1 GUCD1 LRRC75B UPB1 SPECC1L-ADORA2A
nsv9884	Chr.22:24415625 - 24662249 on Build GRCh38	Gain+Loss	ADORA2A-AS1 ADORA2A SNRPD3 SPECC1L POM121L10P GGT1 GUCD1 LRRC75B UPB1 BCRP3 SPECC1L-ADORA2A
esv3575443	Chr.22:23348201 - 24670505 on Build GRCh38	Gain	CES5AP1 ZDHHC8P1 RGL4 PCAT14 SLC2A11 ZNF70 SPECC1L-ADORA2A POM121L9P MMP11 LOC388882 VPREB3 DDT ADORA2A-AS1 ADORA2A MIF-AS1 SPECC1L GSTT2B DDTL DERL3 SUSD2 UPB1 DRICH1 IGLL1 LOC107985559 BCRP3 CABIN1 POM121L10P GGT1 LRRC75B LOC107985555 GUSBP11 MIF GSTT2 SMARCB1 SNRPD3 LOC100652871 C22orf15 GUCD1 GSTTP1 GGT5 LOC101929374 CHCHD10
nsv834160	Chr.22:24329972 - 24507687 on Build GRCh38	Gain	ADORA2A-AS1 ADORA2A SPECC1L UPB1 SPECC1L-ADORA2A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

adenosine receptor signaling pathway
cAMP biosynthetic process
phagocytosis
apoptotic process
inflammatory response
cellular defense response
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
cell-cell signaling
central nervous system development
blood coagulation
sensory perception
blood circulation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
cellular protein metabolic process

Function(s)

G-protein coupled adenosine receptor activity
protein binding
enzyme binding
identical protein binding