Hs01928784_cn

• Gene Symbol: ADORA2A
• Assay Reference Genome Location: Chr.22:24442363 on build GRCh38
• Cytoband: 22q11.23

Target Gene Details

• Entrez Gene ID: 135
• Gene Name: adenosine A2a receptor
• Gene Aliases: A2aR, ADORA2, RDC8
• Location: Chr.22:24423597-24442360 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A	NM_000675.5			NP_000666.2
	NM_001278497.1			NP_001265426.1
	NM_001278498.1			NP_001265427.1
	NM_001278499.1			NP_001265428.1
	NM_001278500.1			NP_001265429.1
	NR_103543.1
	NR_103544.1
	AK123058.1
	BC013780.1			AAH13780.1
	CA307692.1
	M97370.1			AAA58356.1

Target Gene Details

• Entrez Gene ID: 646023
• Gene Name: ADORA2A antisense RNA 1
• Gene Aliases: C22orf45
• Location: Chr.22:24429206-24495074 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A-AS1	NR_028483.2
	NR_028484.2
	DB449907.2

Target Gene Details

• Entrez Gene ID: 101730217
• Gene Name: SPECC1L-ADORA2A readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.22:24270817-24442360 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPECC1L-ADORA2A	NR_103546.1
	AB209022.1			BAD92259.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2724068	Chr.22:24288741 - 24669870 on Build GRCh38	Deletion	ADORA2A ADORA2A-AS1 LRRC75B GGT1 SPECC1L GUCD1 BCRP3 POM121L10P SPECC1L-ADORA2A UPB1 SNRPD3
dgv8039n54	Chr.22:23323169 - 24601506 on Build GRCh38	Gain	LRRC75B GGT5 C22orf15 GSTT2B SPECC1L-ADORA2A CES5AP1 ADORA2A-AS1 LOC100652871 SLC2A11 PCAT14 IGLL1 GUCD1 MMP11 SMARCB1 GSTT2 GSTTP1 MIF LOC101929374 ZDHHC8P1 GGT1 SUSD2 LOC107985559 SPECC1L CABIN1 RGL4 GUSBP11 DDT SNRPD3 ADORA2A DRICH1 LOC388882 CHCHD10 ZNF70 DDTL LOC107985555 POM121L9P VPREB3 MIF-AS1 DERL3 UPB1
nsv1057819	Chr.22:24290518 - 24624081 on Build GRCh38	Gain	ADORA2A ADORA2A-AS1 LRRC75B GGT1 SPECC1L GUCD1 SPECC1L-ADORA2A UPB1 SNRPD3
nsv526567	Chr.22:23348138 - 24600663 on Build GRCh38	Gain	LRRC75B GGT5 C22orf15 GSTT2B SPECC1L-ADORA2A CES5AP1 ADORA2A-AS1 LOC100652871 SLC2A11 PCAT14 IGLL1 GUCD1 MMP11 SMARCB1 GSTT2 GSTTP1 MIF LOC101929374 ZDHHC8P1 GGT1 SUSD2 LOC107985559 SPECC1L CABIN1 RGL4 GUSBP11 DDT SNRPD3 ADORA2A DRICH1 LOC388882 CHCHD10 ZNF70 DDTL LOC107985555 POM121L9P VPREB3 MIF-AS1 DERL3 UPB1
esv2724041	Chr.22:23315914 - 24669376 on Build GRCh38	Deletion	LRRC75B GGT5 C22orf15 GSTT2B SPECC1L-ADORA2A CES5AP1 ADORA2A-AS1 LOC100652871 SLC2A11 PCAT14 IGLL1 GUCD1 MMP11 SMARCB1 GSTT2 GSTTP1 MIF LOC101929374 ZDHHC8P1 GGT1 SUSD2 LOC107985559 SPECC1L CABIN1 RGL4 BCRP3 GUSBP11 POM121L10P DDT SNRPD3 ADORA2A DRICH1 LOC388882 CHCHD10 ZNF70 BCR DDTL LOC107985555 POM121L9P VPREB3 MIF-AS1 DERL3 UPB1
nsv1055830	Chr.22:24005071 - 24643213 on Build GRCh38	Gain	LRRC75B GGT5 GGT1 SUSD2 SPECC1L CABIN1 BCRP3 SPECC1L-ADORA2A SNRPD3 ADORA2A ADORA2A-AS1 GUCD1 POM121L9P UPB1 GSTTP1
esv3893463	Chr.22:24009046 - 24601506 on Build GRCh38	Gain	LRRC75B GGT5 GGT1 SUSD2 SPECC1L CABIN1 SPECC1L-ADORA2A SNRPD3 ADORA2A ADORA2A-AS1 GUCD1 POM121L9P UPB1
dgv4528n100	Chr.22:23322244 - 24682765 on Build GRCh38	Gain	LRRC75B GGT5 C22orf15 GSTT2B SPECC1L-ADORA2A CES5AP1 ADORA2A-AS1 LOC100652871 SLC2A11 PCAT14 IGLL1 GUCD1 MMP11 SMARCB1 GSTT2 GSTTP1 MIF LOC101929374 ZDHHC8P1 GGT1 SUSD2 LOC107985559 SPECC1L CABIN1 RGL4 BCRP3 GUSBP11 POM121L10P DDT SNRPD3 ADORA2A DRICH1 LOC388882 CHCHD10 ZNF70 DDTL LOC107985555 POM121L9P VPREB3 MIF-AS1 DERL3 UPB1
nsv588744	Chr.22:24285587 - 24617379 on Build GRCh38	Gain	ADORA2A ADORA2A-AS1 LRRC75B GGT1 SPECC1L GUCD1 SPECC1L-ADORA2A UPB1 SNRPD3
esv3575443	Chr.22:23348201 - 24670505 on Build GRCh38	Gain	LRRC75B GGT5 C22orf15 GSTT2B SPECC1L-ADORA2A CES5AP1 ADORA2A-AS1 LOC100652871 SLC2A11 PCAT14 IGLL1 GUCD1 MMP11 SMARCB1 GSTT2 GSTTP1 MIF LOC101929374 ZDHHC8P1 GGT1 SUSD2 LOC107985559 SPECC1L CABIN1 RGL4 BCRP3 GUSBP11 POM121L10P DDT SNRPD3 ADORA2A DRICH1 LOC388882 CHCHD10 ZNF70 DDTL LOC107985555 POM121L9P VPREB3 MIF-AS1 DERL3 UPB1
nsv9884	Chr.22:24415625 - 24662249 on Build GRCh38	Gain+Loss	ADORA2A ADORA2A-AS1 LRRC75B GGT1 SPECC1L GUCD1 BCRP3 POM121L10P SPECC1L-ADORA2A UPB1 SNRPD3
nsv834160	Chr.22:24329972 - 24507687 on Build GRCh38	Gain	ADORA2A ADORA2A-AS1 SPECC1L SPECC1L-ADORA2A UPB1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

adenosine receptor signaling pathway
cAMP biosynthetic process
phagocytosis
apoptotic process
inflammatory response
cellular defense response
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
cell-cell signaling
central nervous system development
blood coagulation
sensory perception
blood circulation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
cellular protein metabolic process

Function(s)

G-protein coupled adenosine receptor activity
protein binding
enzyme binding
identical protein binding