Hs01933203_cn

• Gene Symbol: UBR1
• Assay Reference Genome Location: Chr.15:42945408 on build GRCh38
• Cytoband: 15q15.2

Target Gene Details

• Entrez Gene ID: 197131
• Gene Name: ubiquitin protein ligase E3 component n-recognin 1
• Gene Aliases: JBS
• Location: Chr.15:42942897-43106088 on Build GRCh38
• Assay Gene Location: Within Exon 47

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBR1	NM_174916.2	47	5237	NP_777576.1
	AF525401.1			AAO14997.1
	AK127478.1	11	1092
	AY061886.1	47	5171	AAL32103.1
	BC113505.1	47	5249
	BC113507.1	47	5249
	BX648400.1	19	2049

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525461	Chr.15:42770350 - 43189929 on Build GRCh38	Loss	TMEM62 TTBK2 CCNDBP1 UBR1
nsv569241	Chr.15:42908911 - 43230724 on Build GRCh38	Loss	TMEM62 TTBK2 CCNDBP1 UBR1 EPB42
esv3636283	Chr.15:42857607 - 42985063 on Build GRCh38	Gain	TTBK2 UBR1
nsv515876	Chr.15:42824708 - 43153107 on Build GRCh38	Gain+Loss	TMEM62 TTBK2 UBR1
esv3636285	Chr.15:42907489 - 42978310 on Build GRCh38	Gain	TTBK2 UBR1
nsv1036512	Chr.15:42872708 - 42982333 on Build GRCh38	Gain	TTBK2 UBR1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

protein ubiquitination
negative regulation of TOR signaling
cellular response to leucine
ubiquitin-dependent protein catabolic process via the N-end rule pathway

Function(s)

zinc ion binding
ligase activity
ubiquitin protein ligase activity
leucine binding