Hs01937962_cn

• Gene Symbol: CYB561D2
• Assay Reference Genome Location: Chr.3:50359449 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 11068
• Gene Name: cytochrome b561 family member D2
• Gene Aliases: 101F6, TSP10, XXcos-LUCA11.4
• Location: Chr.3:50350695-50368197 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYB561D2	NR_111912.1
	BM852873.1

Target Gene Details

• Entrez Gene ID: 11070
• Gene Name: transmembrane protein 115
• Gene Aliases: PL6
• Location: Chr.3:50354749-50359508 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TMEM115	NM_007024.4	1	60	NP_008955.1
	AK314166.1	1	67
	BC011948.1			AAH11948.1
	BC017367.2			AAH17367.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3584502	Chr.3:50327055 - 50622310 on Build GRCh38	Gain	TUSC2 RASSF1-AS1 TMEM115 HEMK1 MAPKAPK3 NPRL2 CYB561D2 CACNA2D2 ZMYND10 C3orf18 CISH RASSF1
dgv8317n54	Chr.3:50206077 - 50383123 on Build GRCh38	Loss	HYAL3 NAT6 TMEM115 MIR5787 NPRL2 CYB561D2 CACNA2D2 HYAL1 RASSF1 HYAL2 TUSC2 LSMEM2 RASSF1-AS1 IFRD2 GNAI2 SEMA3B-AS1 ZMYND10 MIR6872 SLC38A3 SEMA3B
nsv834693	Chr.3:50251400 - 50470533 on Build GRCh38	Loss	HYAL3 NAT6 TMEM115 NPRL2 CYB561D2 CACNA2D2 HYAL1 RASSF1 HYAL2 TUSC2 LSMEM2 RASSF1-AS1 IFRD2 GNAI2 SEMA3B-AS1 ZMYND10 MIR6872 SEMA3B
nsv523662	Chr.3:50107518 - 50547568 on Build GRCh38	Loss	SEMA3F MIR5787 NPRL2 CYB561D2 HYAL1 RASSF1 HYAL2 TUSC2 LSMEM2 RASSF1-AS1 IFRD2 SLC38A3 SEMA3B RBM5 SEMA3F-AS1 HYAL3 NAT6 MIR566 TMEM115 LOC107986035 CACNA2D2 GNAT1 GNAI2 SEMA3B-AS1 ZMYND10 MIR6872
nsv470561	Chr.3:50121341 - 50547568 on Build GRCh38	Loss	SEMA3F MIR5787 NPRL2 CYB561D2 HYAL1 RASSF1 HYAL2 TUSC2 LSMEM2 RASSF1-AS1 IFRD2 SLC38A3 SEMA3B SEMA3F-AS1 HYAL3 NAT6 MIR566 TMEM115 LOC107986035 CACNA2D2 GNAT1 GNAI2 SEMA3B-AS1 ZMYND10 MIR6872
nsv460531	Chr.3:50210391 - 50399396 on Build GRCh38	Loss	HYAL3 NAT6 TMEM115 MIR5787 NPRL2 CYB561D2 CACNA2D2 HYAL1 RASSF1 HYAL2 TUSC2 LSMEM2 RASSF1-AS1 IFRD2 GNAI2 SEMA3B-AS1 ZMYND10 MIR6872 SLC38A3 SEMA3B
nsv954855	Chr.3:50152468 - 50439169 on Build GRCh38	Deletion	SEMA3F MIR5787 NPRL2 CYB561D2 HYAL1 RASSF1 HYAL2 TUSC2 LSMEM2 RASSF1-AS1 IFRD2 SLC38A3 SEMA3B SEMA3F-AS1 HYAL3 NAT6 MIR566 TMEM115 LOC107986035 CACNA2D2 GNAT1 GNAI2 SEMA3B-AS1 ZMYND10 MIR6872

More Information

Additional Information:

For this assay, SNP(s) [rs142285269] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

vesicle coat protein

Gene Ontology Categories:

Process(es)

oxidation-reduction process
protein glycosylation
ER to Golgi vesicle-mediated transport
retrograde vesicle-mediated transport, Golgi to ER
negative regulation of cell proliferation
protein transport

Function(s)

metal ion binding
molecular_function
protein binding
identical protein binding