Hs01952965_cn

• Gene Symbol: MAP3K6
• Assay Reference Genome Location: Chr.1:27358262 on build GRCh38
• Cytoband: 1p36.11

Target Gene Details

• Entrez Gene ID: 9064
• Gene Name: mitogen-activated protein kinase kinase kinase 6
• Gene Aliases: ASK2, MAPKKK6, MEKK6
• Location: Chr.1:27355179-27368037 on Build GRCh38
• Assay Gene Location: Within Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAP3K6	NM_001297609.1	20	3079	NP_001284538.1
	NM_004672.4	21	3103	NP_004663.3
	XM_017002771.1	19	2484	XP_016858260.1
	AB167411.1	21	2834	BAD12485.1
	AB208805.1	20	2548	BAD92042.1
	AF100318.1	18	2248	AAD05304.1
	BC015914.1	17	2005	AAH15914.1
	BC109032.2	12	1382	AAI09033.1
	BC129950.1	13	1533
	BC129951.1	13	1533

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526051	Chr.1:27284255 - 27445496 on Build GRCh38	Gain	FCN3 TMEM222 WASF2 SYTL1 MAP3K6 ACTG1P20 CD164L2 GPR3 WDTC1
nsv516766	Chr.1:27335744 - 27405147 on Build GRCh38	Loss	FCN3 TMEM222 WASF2 SYTL1 MAP3K6 CD164L2 GPR3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
protein phosphorylation
signal transduction
activation of JUN kinase activity

Function(s)

magnesium ion binding
MAP kinase kinase kinase activity
ATP binding