Hs01982150_cn

• Gene Symbol: AMER3
• Assay Reference Genome Location: Chr.2:130764170 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 205147
• Gene Name: APC membrane recruitment protein 3
• Gene Aliases: FAM123C
• Location: Chr.2:130754475-130768134 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AMER3	NM_001105193.1	2	2272	NP_001098663.1
	NM_001105194.1	2	2208	NP_001098664.1
	NM_001105195.1	2	2205	NP_001098665.1
	NM_152698.2	2	2288	NP_689911.2
	XM_011510793.2	2	3314	XP_011509095.1
	AK095696.1	2	2252	BAC04612.1
	AK289525.1	2	2357
	AK291424.1	2	2252
	BC113445.1	2	2165
	BC113447.1	2	2165
	BC143806.1	2	2162

Target Gene Details

• Entrez Gene ID: 653269
• Gene Name: POTE ankyrin domain family member I
• Gene Aliases: POTE2beta
• Location: Chr.2:130462245-131626428 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POTEI

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv4074n100	Chr.2:130550793 - 131291209 on Build GRCh38	Gain	GPR148 CYP4F30P ARHGEF4 FAM168B CFC1 POTEE POTEI POTEJ TISP43 AMER3 LOC440910 PLEKHB2
dgv731e199	Chr.2:130678437 - 131300107 on Build GRCh38	Deletion	GPR148 CYP4F30P ARHGEF4 FAM168B POTEE POTEI AMER3 LOC440910 PLEKHB2
esv2670824	Chr.2:130625264 - 131605218 on Build GRCh38	Deletion	CYP4F30P MIR4784 POTEI POTEJ MZT2A LINC01120 WTH3DI LOC150776 POTEKP AMER3 NOC2LP2 GPR148 ARHGEF4 FAM168B POTEE CCDC74A LOC440910 TUBA3D PLEKHB2
nsv583136	Chr.2:130730100 - 130846832 on Build GRCh38	Loss	GPR148 ARHGEF4 POTEI AMER3
nsv1014723	Chr.2:130720375 - 131379551 on Build GRCh38	Loss	GPR148 ARHGEF4 FAM168B POTEE POTEI WTH3DI AMER3 LOC440910 PLEKHB2
esv3893337	Chr.2:130722838 - 131194387 on Build GRCh38	Loss	GPR148 ARHGEF4 FAM168B POTEI AMER3 PLEKHB2
dgv616e201	Chr.2:130674635 - 131312550 on Build GRCh38	Deletion	GPR148 CYP4F30P ARHGEF4 FAM168B POTEE POTEI AMER3 LOC440910 PLEKHB2
nsv583135	Chr.2:130724905 - 131194388 on Build GRCh38	Loss	GPR148 ARHGEF4 FAM168B POTEI AMER3 PLEKHB2
nsv524021	Chr.2:130724906 - 131553515 on Build GRCh38	Loss	MIR4784 POTEI MZT2A LINC01120 WTH3DI LOC150776 AMER3 NOC2LP2 GPR148 ARHGEF4 FAM168B POTEE CCDC74A LOC440910 TUBA3D PLEKHB2
nsv10175	Chr.2:130762563 - 130766308 on Build GRCh38	Loss	POTEI AMER3
esv2760576	Chr.2:130634172 - 131521752 on Build GRCh38	Gain+Loss	CYP4F30P MIR4784 POTEI POTEJ MZT2A LINC01120 WTH3DI LOC150776 AMER3 NOC2LP2 GPR148 ARHGEF4 FAM168B POTEE LOC440910 TUBA3D PLEKHB2
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	CYP4F30P CFC1 MZT2A FAR2P1 NOC2LP2 GPR39 FAR2P2 POTEF LOC440910 LOC646743 CCDC115 TUBA3E CFC1B POTEKP ANKRD30BL C2orf27A SMPD4 RAB6C LOC107985778 MED15P9 LINC01087 TUBA3D LOC100507460 MIR4784 POTEI RAB6C-AS1 LOC389033 LINC01120 WTH3DI PTPN18 LOC150776 ZNF806 GPR148 ARHGEF4 FAM168B CCDC74A LOC101927924 MZT2B IMP4 NOC2LP1 CYP4F62P PLEKHB2 FAM201B POTEJ CCDC74B TISP43 AMER3 POTEE MIR663B C2orf27B
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	CYP4F30P CFC1 POTEI RAB6C-AS1 LOC389033 FAR2P1 PTPN18 GPR148 ARHGEF4 LOC101927924 MZT2B FAR2P2 IMP4 NOC2LP1 CYP4F62P POTEF LOC646743 CCDC115 TUBA3E POTEJ CCDC74B CFC1B TISP43 AMER3 SMPD4 RAB6C LOC107985778 MED15P9

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

Wnt signaling pathway
anatomical structure development
regulation of canonical Wnt signaling pathway

Function(s)

protein binding
phosphatidylinositol-4,5-bisphosphate binding
beta-catenin binding