Hs01990329_cn

• Gene Symbol: POLR3K
• Assay Reference Genome Location: Chr.16:53596 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 51728
• Gene Name: RNA polymerase III subunit K
• Gene Aliases: C11, C11-RNP3, My010, RPC10, RPC11, RPC12.5
• Location: Chr.16:46979-53632 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR3K	NM_016310.4	1	37	NP_057394.3
	AF051316.1			AAF18268.1
	AF060223.1			AAG43123.1
	BC011932.2			AAH11932.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv518291	Chr.16:47354 - 254515 on Build GRCh38	Loss	FAM234A HBA2 LUC7L HBQ1 POLR3K MPG RHBDF1 SNRNP25 HBZ HBA1 HBM NPRL3
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	CRAMP1 UNKL LOC106660606 LOC729652 SNRNP25 E4F1 NTN3 MIR3180-5 LOC105371047 PIGQ TELO2 SNHG9 TPSD1 METTL26 CLCN7 C16orf59 CACNA1H FAM173A ECI1 GNG13 AXIN1 NARFL TSR3 MLST8 SNORD60 PRSS27 RPL3L NTHL1 POLR3K SNORA10 SNORA78 ARHGDIG LOC105371184 LOC107987233 MCRIP2 MIR6511B1 HBQ1 WASIR2 LOC105371046 RNF151 GFER MSLN ERVK13-1 HBM HS3ST6 WDR90 FAM234A ABCA3 MEIOB MIR1225 RPL23AP5 LMF1-AS1 MRPS34 HAGHL RHBDF1 RPUSD1 CCDC78 MIR940 MIR5587 MIR662 METRN EME2 PRR25 BRICD5 LOC105371049 RAB40C CAPN15 LOC107984876 SNHG19 IGFALS SYNGR3 LOC101929280 STUB1 TPSG1 NOXO1 SLC9A3R2 LOC105371045 MSRB1 ATP6V0C LOC652276 PTX4 HBZ NUBP2 MIR4717 C16orf91 TPSAB1 DECR2 MIR3176 MAPK8IP3 WFIKKN1 MIR3178 SSTR5 IFT140 FBXL16 TMEM204 RPS2 PRR35 ABCA17P RHBDL1 JMJD8 LOC105371038 UBE2I BAIAP3 CCDC154 CCNF RNPS1 SPSB3 TBC1D24 SOX8 PRSS29P TSC2 MIR6768 HBA2 MIR6767 MIR3677 PGP PDIA2 ZNF598 MPG DNASE1L2 PKD1 MRPL28 NME4 MIR4516 NPRL3 LOC100134368 NME3 NDUFB10 HAGH RGS11 TPSB2 SNORA64 RAB26 RHOT2 PDPK1 LOC100287175 GNPTG RAB11FIP3 LINC00254 LINC00235 SSTR5-AS1 MIR6859-4 FLJ42627 KCTD5 TBL3 HN1L CASKIN1 LUC7L NPW CEMP1 LMF1 HBA1 TMEM8A WDR24 AMDHD2 MIR3177 FAHD1 CHTF18 TRAF7 C1QTNF8 NHLRC4 DDX11L10
nsv1044732	Chr.16:35815 - 60707 on Build GRCh38	Loss	POLR3K RHBDF1 SNRNP25
dgv2688n100	Chr.16:10765 - 80854 on Build GRCh38	Gain	WASIR2 POLR3K MPG RHBDF1 SNRNP25 MIR6859-4 DDX11L10
esv2760065	Chr.16:31052 - 143601 on Build GRCh38	Gain	POLR3K MPG RHBDF1 SNRNP25 HBZ NPRL3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase, RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase III promoter
termination of RNA polymerase III transcription
positive regulation of type I interferon production
innate immune response
defense response to virus

Function(s)

RNA polymerase III activity
nucleic acid binding
DNA-directed RNA polymerase activity
zinc ion binding