Hs02023857_cn

• Gene Symbol: MAP3K6
• Assay Reference Genome Location: Chr.1:27362898 on build GRCh38
• Cytoband: 1p36.11

Target Gene Details

• Entrez Gene ID: 9064
• Gene Name: mitogen-activated protein kinase kinase kinase 6
• Gene Aliases: ASK2, MAPKKK6, MEKK6
• Location: Chr.1:27355179-27368037 on Build GRCh38
• Assay Gene Location: Overlaps Intron 6 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAP3K6	NM_001297609.1			NP_001284538.1
	NM_004672.4			NP_004663.3
	XM_017002771.1			XP_016858260.1
	XM_017002772.1			XP_016858261.1
	AB167411.1			BAD12485.1
	AB208805.1			BAD92042.1
	AF100318.1			AAD05304.1
	BC015914.1			AAH15914.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526051	Chr.1:27284255 - 27445496 on Build GRCh38	Gain	WASF2 ACTG1P20 WDTC1 MAP3K6 GPR3 SYTL1 CD164L2 FCN3 TMEM222
nsv516766	Chr.1:27335744 - 27405147 on Build GRCh38	Loss	WASF2 MAP3K6 GPR3 SYTL1 CD164L2 FCN3 TMEM222

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
protein phosphorylation
signal transduction
activation of JUN kinase activity

Function(s)

magnesium ion binding
MAP kinase kinase kinase activity
ATP binding