Hs02028343_cn

• Gene Symbol: OTULIN
• Assay Reference Genome Location: Chr.5:14673657 on build GRCh38
• Cytoband: 5p15.2

Target Gene Details

• Entrez Gene ID: 90268
• Gene Name: OTU deubiquitinase with linear linkage specificity
• Gene Aliases: FAM105B, GUM
• Location: Chr.5:14660794-14716552 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
OTULIN	NM_138348.4			NP_612357.4
	XM_011514151.2			XP_011512453.1
	XM_011514152.2			XP_011512454.1
	XM_011514154.2			XP_011512456.1
	XM_017010015.1			XP_016865504.1
	BC015392.1			AAH15392.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1026914	Chr.5:14237673 - 14751479 on Build GRCh38	Gain	SNORD141B LOC100130744 TRIO ANKH FAM105A OTULIN
nsv830211	Chr.5:14474566 - 14675667 on Build GRCh38	Loss	SNORD141B TRIO FAM105A OTULIN
nsv1018187	Chr.5:14385055 - 15126994 on Build GRCh38	Gain	SNORD141B LOC100130744 TRIO MIR4637 ANKH FAM105A OTULIN

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

sprouting angiogenesis
regulation of tumor necrosis factor-mediated signaling pathway
negative regulation of NF-kappaB transcription factor activity
innate immune response
negative regulation of inflammatory response
canonical Wnt signaling pathway
nucleotide-binding oligomerization domain containing 2 signaling pathway
protein linear deubiquitination

Function(s)

thiol-dependent ubiquitin-specific protease activity
protein binding
cysteine-type peptidase activity