Hs02045768_cn

• Gene Symbol: TOB2
• Assay Reference Genome Location: Chr.22:41446954 on build GRCh38
• Cytoband: 22q13.2

Target Gene Details

• Entrez Gene ID: 10766
• Gene Name: transducer of ERBB2, 2
• Gene Aliases: APRO5, TOB4, TOBL, TROB2
• Location: Chr.22:41433488-41448230 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TOB2	NM_016272.3	1	70	NP_057356.1
	XM_005261315.2	1	1277	XP_005261372.1
	XM_017028539.1	1	1277	XP_016884028.1
	BM453650.1	1	70

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv516925	Chr.22:41252498 - 41585953 on Build GRCh38	Loss	LOC100996598 TEF PMM1 ZC3H7B TOB2 LOC105373044 RANGAP1 CSDC2 POLR3H ACO2 PHF5A MIR6889
nsv834207	Chr.22:41282650 - 41463790 on Build GRCh38	Loss	LOC100996598 TEF ZC3H7B TOB2 RANGAP1 PHF5A
nsv834208	Chr.22:41363612 - 41554028 on Build GRCh38	Loss	LOC100996598 TEF TOB2 LOC105373044 POLR3H ACO2 PHF5A
nsv459888	Chr.22:41231539 - 41454496 on Build GRCh38	Gain	LOC100996598 TEF ZC3H7B TOB2 RANGAP1 CHADL MIR6889
nsv524585	Chr.22:40993505 - 41794305 on Build GRCh38	Loss	EP300 LOC100996598 PMM1 ZC3H7B MEI1 XRCC6 RANGAP1 CSDC2 POLR3H MIR1281 SNU13 PHF5A MIR6889 TEF DESI1 TOB2 LOC105373044 CHADL SNORD140 ACO2 EP300-AS1 L3MBTL2 C22orf46

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

female gamete generation
negative regulation of cell proliferation
regulation of gene expression
negative regulation of osteoclast differentiation
positive regulation of ossification

Function(s)

protein binding
vitamin D receptor binding