Hs02055193_cn

• Gene Symbol: CENPU
• Assay Reference Genome Location: Chr.4:184694238 on build GRCh38
• Cytoband: 4q35.1

Target Gene Details

• Entrez Gene ID: 79682
• Gene Name: centromere protein U
• Gene Aliases: CENP50, CENPU50, KLIP1, MLF1IP, PBIP1
• Location: Chr.4:184694065-184734132 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CENPU	NM_024629.3	13	2377	NP_078905.2
	NR_104593.1	12	2315
	XM_005263218.4	13	2412	XP_005263275.2
	AA761728.1	1	171
	AF516710.1	14	2794	AAQ08228.1
	AW440254.1	1	178
	BX355581.2	1	120

Target Gene Details

• Entrez Gene ID: 201973
• Gene Name: primase and DNA directed polymerase
• Gene Aliases: CCDC111, MYP22
• Location: Chr.4:184649613-184694959 on Build GRCh38
• Assay Gene Location: Overlaps Intron 14 - Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRIMPOL	NM_001300767.1			NP_001287696.1
	NM_001300768.1			NP_001287697.1
	NM_152683.3			NP_689896.1
	XM_011531719.1			XP_011530021.1
	XM_011531720.1			XP_011530022.1
	XM_011531721.2			XP_011530023.1
	XM_011531723.1			XP_011530025.1
	XM_011531724.2			XP_011530026.1
	XM_011531725.1			XP_011530027.1
	XM_011531726.2			XP_011530028.1
	XM_011531729.1			XP_011530031.1
	XM_011531730.2			XP_011530032.1
	XM_017007864.1			XP_016863353.1
	XM_017007865.1			XP_016863354.1
	XM_017007866.1			XP_016863355.1
	XM_017007867.1			XP_016863356.1
	XM_017007868.1			XP_016863357.1
	XM_017007869.1			XP_016863358.1
	XM_017007870.1			XP_016863359.1
	XM_017007871.1			XP_016863360.1
	XM_017007872.1			XP_016863361.1
	XM_017007873.1			XP_016863362.1
	XM_017007874.1			XP_016863363.1
	XM_017007875.1			XP_016863364.1
	AK057729.1			BAB71553.1
	BC064600.1			AAH64600.1
	BX647575.1			CAI46079.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv830168	Chr.4:184626297 - 184801578 on Build GRCh38	Loss	PRIMPOL CASP3 SLED1 ACSL1 CENPU
nsv1026074	Chr.4:184384963 - 184780663 on Build GRCh38	Gain	PRIMPOL LVCAT8 CASP3 ACSL1 IRF2 CENPU

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
sister chromatid cohesion
viral process
CENP-A containing nucleosome assembly
chordate embryonic development
mitochondrial DNA replication
DNA replication, synthesis of RNA primer
response to UV
translesion synthesis
replication fork processing

Function(s)

protein binding
chromatin binding
DNA-directed DNA polymerase activity
DNA primase activity
manganese ion binding