Hs02100448_cn

• Gene Symbol: CTSK
• Assay Reference Genome Location: Chr.1:150806709 on build GRCh38
• Cytoband: 1q21.3

Target Gene Details

• Entrez Gene ID: 1513
• Gene Name: cathepsin K
• Gene Aliases: CTS02, CTSO, CTSO1, CTSO2, PKND, PYCD
• Location: Chr.1:150796208-150808441 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CTSK	NM_000396.3			NP_000387.1
	AK130134.1
	AK308229.1
	AK312880.1
	AU118043.1
	AU119985.1
	AY429530.1
	BC016058.1			AAH16058.1
	CR541675.1			CAG46476.1
	CR541719.1			CAG46520.1
	DA251123.1
	S79895.1			AAB35521.1
	U13665.1			AAA65233.1
	U20280.1			AAA95998.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv437169	Chr.1:150765721 - 150844410 on Build GRCh38	Loss	CTSS CTSK ARNT
nsv2788	Chr.1:150782858 - 150828309 on Build GRCh38	Deletion	CTSK ARNT

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cysteine protease

Gene Ontology Categories:

Process(es)

intramembranous ossification
toll-like receptor signaling pathway
proteolysis
extracellular matrix disassembly
collagen catabolic process
bone resorption
proteolysis involved in cellular protein catabolic process
regulation of mitophagy
positive regulation of protein targeting to mitochondrion

Function(s)

fibronectin binding
cysteine-type endopeptidase activity
serine-type endopeptidase activity
protein binding
collagen binding
cysteine-type peptidase activity
proteoglycan binding