Hs02133314_cn

• Gene Symbol: LPAR1
• Assay Reference Genome Location: Chr.9:110873800 on build GRCh38
• Cytoband: 9q31.3

Target Gene Details

• Entrez Gene ID: 1902
• Gene Name: lysophosphatidic acid receptor 1
• Gene Aliases: EDG2, GPR26, Gpcr26, LPA1, Mrec1.3, VZG1, edg-2, rec.1.3, vzg-1
• Location: Chr.9:110873252-111039259 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LPAR1	NM_001401.3			NP_001392.2
	NM_057159.2			NP_476500.1
	XM_005251781.3	5	3287	XP_005251838.1
	XM_005251782.3	5	3381	XP_005251839.1
	XM_017014383.1	5	3181	XP_016869872.1
	XM_017014384.1	6	3555	XP_016869873.1
	XM_017014385.1	7	3148	XP_016869874.1
	XM_017014386.1	7	3448	XP_016869875.1
	XM_017014387.1	7	3184	XP_016869876.1
	XM_017014388.1	7	3367	XP_016869877.1
	XM_017014389.1	6	3110	XP_016869878.1
	XM_017014390.1	7	3145	XP_016869879.1
	XM_017014391.1	7	3169	XP_016869880.1
	XM_017014392.1	6	3412	XP_016869881.1
	XM_017014393.1	7	3208	XP_016869882.1
	XM_017014394.1	6	3337	XP_016869883.1
	XM_017014395.1	6	3165	XP_016869884.1
	XM_017014396.1	5	3107	XP_016869885.1
	XM_017014397.1	6	3038	XP_016869886.1
	XM_017014398.1	6	3281	XP_016869887.1
	XM_017014399.1	6	3036	XP_016869888.1
	XM_017014400.1	7	3397	XP_016869889.1
	XM_017014401.1	6	3068	XP_016869890.1
	XM_017014402.1	6	3125	XP_016869891.1
	XM_017014403.1	7	3123	XP_016869892.1
	XM_017014404.1	5	3321	XP_016869893.1
	XM_017014405.1	7	3310	XP_016869894.1
	XM_017014406.1	6	3044	XP_016869895.1
	XM_017014407.1	6	3100	XP_016869896.1
	BC030615.2			AAH30615.1
	BC036034.1	5	3101	AAH36034.1

More Information

Additional Information:

For this assay, SNP(s) [rs148202320] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, non-DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

activation of MAPK activity
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
activation of phospholipase C activity
positive regulation of cytosolic calcium ion concentration
regulation of cell shape
negative regulation of neuron projection development
oligodendrocyte development
cerebellum development
optic nerve development
corpus callosum development
negative regulation of cAMP biosynthetic process
bleb assembly
positive regulation of Rho protein signal transduction
myelination
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAPK cascade
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
positive regulation of stress fiber assembly
cell chemotaxis
positive regulation of dendritic spine development
cellular response to oxygen levels
positive regulation of smooth muscle cell chemotaxis
cellular response to 1-oleoyl-sn-glycerol 3-phosphate

Function(s)

G-protein alpha-subunit binding
G-protein coupled receptor activity
protein binding
PDZ domain binding
lysophosphatidic acid binding
lysophosphatidic acid receptor activity