Hs02177256_cn

• Gene Symbol: GCN1
• Assay Reference Genome Location: Chr.12:120129351 on build GRCh38
• Cytoband: 12q24.23

Target Gene Details

• Entrez Gene ID: 10985
• Gene Name: GCN1, eIF2 alpha kinase activator homolog
• Gene Aliases: GCN1L, GCN1L1, PRIC295
• Location: Chr.12:120127210-120194710 on Build GRCh38
• Assay Gene Location: Within Exon 57

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GCN1	NM_006836.1	57	7828	NP_006827.1
	BC021129.1	6	700	AAH21129.1
	BC032335.1	6	655	AAH32335.1
	BC046177.1	3	371	AAH46177.1
	BC064346.1	5	544	AAH64346.1
	BC153881.1	57	7828
	D86973.2	57	7828
	U77700.1	35	5293	AAC51648.1
	U88836.1	18	2786	AAD00655.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv560433	Chr.12:120095892 - 120238287 on Build GRCh38	Loss	PXN-AS1 GCN1 MIR4498 RAB35 PXN RPLP0

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

translation
regulation of translation
positive regulation of kinase activity
cellular response to amino acid starvation
positive regulation of transcription from RNA polymerase II promoter in response to stress
regulation of protein kinase activity
cell-cell adhesion
cellular response to leucine starvation

Function(s)

translation factor activity, RNA binding
protein kinase regulator activity
protein kinase binding
ribosome binding
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion