Hs02190163_cn

• Gene Symbol: DCLRE1B
• Assay Reference Genome Location: Chr.1:113911907 on build GRCh38
• Cytoband: 1p13.2

Target Gene Details

• Entrez Gene ID: 64858
• Gene Name: DNA cross-link repair 1B
• Gene Aliases: APOLLO, SNM1B, SNMIB
• Location: Chr.1:113904619-113914086 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DCLRE1B	NM_001319946.1	3	1443	NP_001306875.1
	NM_001319947.1	4	1357	NP_001306876.1
	NM_022836.3	4	1609	NP_073747.1
	AF306691.1
	AF306692.1	3	984
	AK022872.1	4	1155	BAB14284.1
	AK024060.1	4	1527	BAB14807.1
	BC029687.1	4	1486	AAH29687.1
	CR936679.1	3	1368

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3587251	Chr.1:113871703 - 113936287 on Build GRCh38	Loss	DCLRE1B BCL2L15 HIPK1-AS1 AP4B1-AS1 PTPN22 HIPK1 AP4B1
esv3587240	Chr.1:113533246 - 114158910 on Build GRCh38	Loss	MAGI3 DCLRE1B OLFML3 BCL2L15 HIPK1-AS1 AP4B1-AS1 SYT6 PTPN22 HIPK1 RSBN1 PHTF1 AP4B1
esv23869	Chr.1:113320330 - 114358495 on Build GRCh38	Loss	MAGI3 DCLRE1B OLFML3 BCL2L15 HIPK1-AS1 AP4B1-AS1 SYT6 PTPN22 HIPK1 RSBN1 PHTF1 AP4B1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

cell cycle checkpoint
telomere maintenance
double-strand break repair via nonhomologous end joining
telomeric loop formation
protection from non-homologous end joining at telomere
telomeric 3' overhang formation
interstrand cross-link repair
nucleic acid phosphodiester bond hydrolysis

Function(s)

damaged DNA binding
protein binding
5'-3' exonuclease activity
5'-3' exodeoxyribonuclease activity