Hs02200221_cn

• Gene Symbol: NOXA1
• Assay Reference Genome Location: Chr.9:137434083 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 10811
• Gene Name: NADPH oxidase activator 1
• Gene Aliases: NY-CO-31, SDCCAG31, p51NOX
• Location: Chr.9:137423372-137434406 on Build GRCh38
• Assay Gene Location: Overlaps Exon 14 - Intron 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NOXA1	NM_001256067.1			NP_001242996.1
	NM_001256068.1			NP_001242997.1
	NM_006647.1			NP_006638.1
	XM_011518158.2			XP_011516460.1
	XM_011518159.1			XP_011516461.1
	XM_011518160.1			XP_011516462.1
	XM_017014220.1			XP_016869709.1
	AB095031.1			BAC76710.1
	AF039697.1			AAC18046.1
	AI860821.1
	AK098341.1
	AY255769.1			AAP13480.1
	AY927790.1			AAY16126.1
	AY927791.1			AAY16127.1
	BC041594.1			AAH41594.1
	BC110840.1			AAI10841.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1049808	Chr.9:137356366 - 137438026 on Build GRCh38	Gain	EXD3 ENTPD8 NOXA1
nsv951208	Chr.9:137379349 - 137467948 on Build GRCh38	Deletion	MIR7114 EXD3 ENTPD8 NOXA1 NSMF PNPLA7
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	NELFB GRIN1 LCNL1 CCDC183-AS1 ENTPD8 C8G RABL6 MIR7114 TMEM210 SSNA1 C9orf139 MIR4292 STPG3 C9orf173-AS1 C9orf172 FBXW5 CYSRT1 PTGDS NRARP EXD3 SAPCD2 LRRC26 NSMF C9orf142 CCDC183 UAP1L1 MAMDC4 FUT7 TPRN DPP7 PRR31 MAN1B1-AS1 NPDC1 PNPLA7 TMEM203 SLC34A3 ENTPD2 CLIC3 PHPT1 MIR3621 FAM166A RNF224 LOC101930307 ANAPC2 RNF208 LCN12 ABCA2 MAN1B1 NOXA1 MIR4479 NDOR1 TOR4A TUBB4B TRAF2 EDF1
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	EXD3 ENTPD8 NOXA1
nsv6771	Chr.9:137412670 - 137444666 on Build GRCh38	Insertion	EXD3 ENTPD8 NOXA1
esv3622034	Chr.9:137433077 - 137439026 on Build GRCh38	Gain	ENTPD8 NOXA1
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	ANAPC2 RNF208 NELFB TMEM203 GRIN1 SLC34A3 CYSRT1 NRARP EXD3 LRRC26 ENTPD8 NOXA1 TPRN MIR3621 FAM166A NDOR1 TOR4A TMEM210 SSNA1 TUBB4B RNF224 STPG3 C9orf173-AS1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator

Gene Ontology Categories:

Process(es)

superoxide metabolic process
regulation of hydrogen peroxide metabolic process
positive regulation of catalytic activity
regulation of respiratory burst

Function(s)

protein binding
superoxide-generating NADPH oxidase activator activity
SH3 domain binding
enzyme binding
Rac GTPase binding