Hs02230514_cn

• Gene Symbol: CHID1
• Assay Reference Genome Location: Chr.11:869899 on build GRCh38
• Cytoband: 11p15.5

Target Gene Details

• Entrez Gene ID: 66005
• Gene Name: chitinase domain containing 1
• Gene Aliases: GL008, SI-CLP, SICLP
• Location: Chr.11:867859-915058 on Build GRCh38
• Assay Gene Location: Within Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHID1	NM_001142674.1	14	1388	NP_001136146.1
	NM_001142675.1	13	1498	NP_001136147.1
	NM_001142676.1	14	1359	NP_001136148.1
	NM_001142677.1	12	1191	NP_001136149.1
	NM_023947.3	13	1284	NP_076436.3
	XM_005253072.2	13	1371	XP_005253129.1
	XM_005253073.4	13	1279	XP_005253130.1
	XM_006718282.2	14	1359	XP_006718345.1
	XM_011520299.1	13	1595	XP_011518601.1
	XM_011520300.1	12	1502	XP_011518602.1
	XM_017018166.1	14	1445	XP_016873655.1
	AF212229.1	14	1322	AAK14915.1
	AK027711.1	13	1233	BAB55316.1
	AK075413.1	14	1295	BAC11603.1
	AK124697.1	13	1860
	AK225025.1	14	1324
	AK225398.1	14	1307
	AK297743.1	13	1365
	AK301245.1
	AY037151.1	12	1152	AAK67632.1
	BC000001.2	14	1308	AAH00001.1
	BC013642.1	11	920	AAH13642.1
	BC095409.1	13	1220	AAH95409.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3625086	Chr.11:860117 - 882352 on Build GRCh38	Loss	TSPAN4 CHID1
dgv1013n100	Chr.11:772982 - 933569 on Build GRCh38	Gain	POLR2L TSPAN4 RPLP2 AP2A2 PNPLA2 CEND1 SLC25A22 CRACR2B PIDD1 LOC171391 SNORA52 PANO1 PDDC1 CHID1 CD151
nsv552887	Chr.11:841284 - 876755 on Build GRCh38	Loss	POLR2L TSPAN4 CHID1
esv2759794	Chr.11:409846 - 1336162 on Build GRCh38	Loss	PTDSS2 POLR2L LMNTD2 TSPAN4 SIGIRR AP2A2 TMEM80 PNPLA2 CEND1 MIR210HG SLC25A22 TOLLIP-AS1 MUC5B CDHR5 TALDO1 SCT MUC5AC MUC2 CRACR2B LOC171391 MIR210 PHRF1 HRAS RASSF7 PANO1 TOLLIP MUC6 CHID1 LRRC56 LOC101059906 EPS8L2 RPLP2 IRF7 DRD4 MIR6744 PIDD1 ANO9 LOC143666 RNH1 SNORA52 DEAF1 LOC101927503 PDDC1 CD151
dgv182e199	Chr.11:349830 - 943372 on Build GRCh38	Deletion	PTDSS2 POLR2L LMNTD2 TSPAN4 SIGIRR AP2A2 TMEM80 PNPLA2 CEND1 MIR210HG SLC25A22 CDHR5 TALDO1 SCT CRACR2B LOC171391 MIR210 PHRF1 HRAS RASSF7 PANO1 CHID1 LRRC56 LOC101059906 EPS8L2 RPLP2 IRF7 PKP3 DRD4 PIDD1 ANO9 LOC143666 RNH1 SNORA52 B4GALNT4 DEAF1 PDDC1 CD151
esv2743878	Chr.11:864732 - 1489652 on Build GRCh38	Deletion	TSPAN4 AP2A2 BRSK2 MIR6744 TOLLIP-AS1 MUC5B MUC5AC MUC2 MOB2 LOC101927503 TOLLIP MUC6 CHID1
nsv1159791	Chr.11:461793 - 909492 on Build GRCh38	Deletion	PTDSS2 POLR2L LMNTD2 TSPAN4 TMEM80 PNPLA2 CEND1 MIR210HG SLC25A22 CDHR5 TALDO1 SCT CRACR2B LOC171391 MIR210 PHRF1 HRAS RASSF7 PANO1 CHID1 LRRC56 LOC101059906 EPS8L2 RPLP2 IRF7 DRD4 PIDD1 LOC143666 RNH1 SNORA52 DEAF1 PDDC1 CD151
nsv552871	Chr.11:766479 - 870446 on Build GRCh38	Loss	POLR2L TSPAN4 RPLP2 PNPLA2 CEND1 SLC25A22 CRACR2B PIDD1 LOC171391 SNORA52 PANO1 PDDC1 CHID1 CD151
nsv469923	Chr.11:378188 - 1302334 on Build GRCh38	Loss	PTDSS2 POLR2L LMNTD2 TSPAN4 SIGIRR AP2A2 TMEM80 PNPLA2 CEND1 MIR210HG SLC25A22 MUC5B CDHR5 TALDO1 SCT MUC5AC MUC2 CRACR2B LOC171391 MIR210 PHRF1 HRAS RASSF7 PANO1 TOLLIP MUC6 CHID1 LRRC56 LOC101059906 EPS8L2 RPLP2 IRF7 PKP3 DRD4 MIR6744 PIDD1 ANO9 LOC143666 RNH1 SNORA52 B4GALNT4 DEAF1 LOC101927503 PDDC1 CD151
dgv175e214	Chr.11:851409 - 1043855 on Build GRCh38	Gain	TSPAN4 AP2A2 MUC6 CHID1
esv2669189	Chr.11:864834 - 1489637 on Build GRCh38	Deletion	TSPAN4 AP2A2 BRSK2 MIR6744 TOLLIP-AS1 MUC5B MUC5AC MUC2 MOB2 LOC101927503 TOLLIP MUC6 CHID1
nsv832044	Chr.11:809019 - 938308 on Build GRCh38	Loss	POLR2L TSPAN4 SNORA52 RPLP2 AP2A2 PNPLA2 CHID1 CD151 CRACR2B PIDD1
nsv1040044	Chr.11:776335 - 900929 on Build GRCh38	Gain+Loss	POLR2L TSPAN4 RPLP2 PNPLA2 CEND1 SLC25A22 CRACR2B PIDD1 LOC171391 SNORA52 PANO1 PDDC1 CHID1 CD151
nsv1048774	Chr.11:816471 - 900929 on Build GRCh38	Gain	POLR2L TSPAN4 PNPLA2 CHID1 CD151 CRACR2B
nsv951272	Chr.11:751201 - 911500 on Build GRCh38	Deletion	POLR2L TSPAN4 RPLP2 PNPLA2 CEND1 SLC25A22 TALDO1 CRACR2B PIDD1 LOC171391 SNORA52 PANO1 PDDC1 CHID1 CD151

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

carbohydrate metabolic process
chitin catabolic process
innate immune response
negative regulation of cytokine production involved in inflammatory response

Function(s)

chitinase activity
protein binding
chitin binding
oligosaccharide binding