Hs02281436_cn

• Gene Symbol: AMER1
• Assay Reference Genome Location: Chr.X:64192746 on build GRCh38
• Cytoband: Xq11.2

Target Gene Details

• Entrez Gene ID: 139285
• Gene Name: APC membrane recruitment protein 1
• Gene Aliases: FAM123B, OSCS, WTX
• Location: Chr.X:64185117-64205744 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AMER1	NM_152424.3	2	814	NP_689637.3
	AK097146.1	2	814	BAC04964.1
	EF186024.1	2	675

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv521560	Chr.X:64063724 - 64245972 on Build GRCh38	Gain	ASB12 AMER1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

Wnt signaling pathway
positive regulation of protein ubiquitination
proteasome-mediated ubiquitin-dependent protein catabolic process
anatomical structure development
bone development
adipose tissue development
regulation of canonical Wnt signaling pathway
mesenchymal cell differentiation involved in kidney development
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
positive regulation of cellular protein catabolic process
beta-catenin destruction complex assembly
beta-catenin destruction complex disassembly

Function(s)

protein binding
phosphatidylinositol-4,5-bisphosphate binding
beta-catenin binding
beta-catenin destruction complex binding