Hs02306752_cn

• Gene Symbol: NOXA1
• Assay Reference Genome Location: Chr.9:137428879 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 10811
• Gene Name: NADPH oxidase activator 1
• Gene Aliases: NY-CO-31, SDCCAG31, p51NOX
• Location: Chr.9:137423372-137434406 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NOXA1	NM_001256067.1			NP_001242996.1
	NM_001256068.1			NP_001242997.1
	NM_006647.1			NP_006638.1
	XM_011518158.2			XP_011516460.1
	XM_011518159.1			XP_011516461.1
	XM_011518160.1			XP_011516462.1
	XM_017014220.1			XP_016869709.1
	AB095031.1			BAC76710.1
	AK098341.1
	AY255769.1			AAP13480.1
	AY927790.1			AAY16126.1
	AY927791.1			AAY16127.1
	BC041594.1			AAH41594.1
	BC110840.1			AAI10841.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1049808	Chr.9:137356366 - 137438026 on Build GRCh38	Gain	NOXA1 EXD3 ENTPD8
nsv951208	Chr.9:137379349 - 137467948 on Build GRCh38	Deletion	NOXA1 EXD3 NSMF PNPLA7 MIR7114 ENTPD8
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	NOXA1 RNF208 SAPCD2 EDF1 CCDC183 TRAF2 MIR4479 CCDC183-AS1 TUBB4B ANAPC2 C8G C9orf142 NSMF UAP1L1 MAN1B1-AS1 LRRC26 PTGDS TOR4A LOC101930307 MAMDC4 NRARP PNPLA7 C9orf139 TPRN GRIN1 NDOR1 RNF224 RABL6 FUT7 CYSRT1 PRR31 CLIC3 DPP7 PHPT1 MIR7114 ABCA2 FBXW5 LCNL1 SLC34A3 EXD3 SSNA1 MIR4292 ENTPD8 C9orf172 MAN1B1 ENTPD2 NPDC1 C9orf173-AS1 MIR3621 LCN12 TMEM210 STPG3 NELFB TMEM203 FAM166A
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	NOXA1 EXD3 ENTPD8
nsv6771	Chr.9:137412670 - 137444666 on Build GRCh38	Insertion	NOXA1 EXD3 ENTPD8
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TOR4A NOXA1 RNF208 CYSRT1 NRARP C9orf173-AS1 MIR3621 TPRN GRIN1 NDOR1 TMEM210 TUBB4B STPG3 ANAPC2 SLC34A3 EXD3 RNF224 NELFB SSNA1 TMEM203 LRRC26 ENTPD8 FAM166A

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator

Gene Ontology Categories:

Process(es)

superoxide metabolic process
regulation of hydrogen peroxide metabolic process
positive regulation of catalytic activity
regulation of respiratory burst

Function(s)

protein binding
superoxide-generating NADPH oxidase activator activity
SH3 domain binding
enzyme binding
Rac GTPase binding