Hs02321651_cn

• Gene Symbol: GFRA3
• Assay Reference Genome Location: Chr.5:138253849 on build GRCh38
• Cytoband: 5q31.2

Target Gene Details

• Entrez Gene ID: 2676
• Gene Name: GDNF family receptor alpha 3
• Gene Aliases: GDNFR3
• Location: Chr.5:138252380-138274564 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GFRA3	NM_001496.3	6	1081	NP_001487.2
	AF051767.1	6	941	AAC24355.1
	AK297693.1	5	942
	AK314022.1	6	982
	AY358997.1	6	978	AAQ89356.1
	AY359037.1	5	989	AAQ89396.1
	BC037951.1	6	966	AAH37951.1
	FJ200487.1	5	848

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3389910	Chr.5:138252164 - 138254262 on Build GRCh38	Duplication	GFRA3

More Information

Additional Information:

For this assay, SNP(s) [rs114764339] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
neuron migration
signal transduction
nervous system development
axon guidance
peripheral nervous system development
positive regulation of GTPase activity
sympathetic nervous system development

Function(s)

Ras guanyl-nucleotide exchange factor activity
receptor binding
axon guidance receptor activity