Hs02327863_cn

• Gene Symbol: ADORA2A
• Assay Reference Genome Location: Chr.22:24432359 on build GRCh38
• Cytoband: 22q11.23

Target Gene Details

• Entrez Gene ID: 135
• Gene Name: adenosine A2a receptor
• Gene Aliases: A2aR, ADORA2, RDC8
• Location: Chr.22:24423597-24442360 on Build GRCh38
• Assay Gene Location: Overlaps Exon 3 - Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A	NM_000675.5			NP_000666.2
	NM_001278497.1			NP_001265426.1
	NM_001278498.1			NP_001265427.1
	NM_001278499.1			NP_001265428.1
	NM_001278500.1			NP_001265429.1
	NR_103543.1
	NR_103544.1
	AK123058.1
	AK289871.1
	AK301420.1
	AK312946.1
	BC013780.1			AAH13780.1
	DA270141.1
	DA781734.1
	DA942067.1
	DA983859.1
	EU036689.1	1	89
	EU036690.1
	EU036691.1
	EU036692.1
	EU036693.1
	EU036694.1
	HY102778.1

Target Gene Details

• Entrez Gene ID: 646023
• Gene Name: ADORA2A antisense RNA 1
• Gene Aliases: C22orf45
• Location: Chr.22:24429206-24495074 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A-AS1	NR_028484.2	5	909
	AK091970.1	1	72
	DB449907.2	5	635

Target Gene Details

• Entrez Gene ID: 101730217
• Gene Name: SPECC1L-ADORA2A readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.22:24270817-24442360 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPECC1L-ADORA2A	NR_103546.1
	AB209022.1			BAD92259.1
	GR939218.1
	GR939229.1
	GR939241.1
	GR939262.1
	GR939274.1
	GR939286.1
	GR939298.1
	GR939310.1
	GR939322.1
	GR939334.1
	GR939358.1
	GR939370.1
	GR939382.1
	GR939394.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv8039n54	Chr.22:23323169 - 24601506 on Build GRCh38	Gain	CABIN1 GGT5 SPECC1L SPECC1L-ADORA2A IGLL1 MMP11 UPB1 MIF-AS1 SNRPD3 GSTTP1 LOC107985559 SUSD2 ZDHHC8P1 LOC107985555 LOC100652871 ZNF70 ADORA2A LRRC75B GUSBP11 LOC101929374 POM121L9P CHCHD10 RGL4 LOC388882 SMARCB1 GSTT2 C22orf15 SLC2A11 VPREB3 DDT CES5AP1 DERL3 GUCD1 DDTL ADORA2A-AS1 GGT1 GSTT2B PCAT14 MIF DRICH1
esv2724068	Chr.22:24288741 - 24669870 on Build GRCh38	Deletion	GUCD1 BCRP3 ADORA2A-AS1 GGT1 SPECC1L SPECC1L-ADORA2A UPB1 ADORA2A SNRPD3 LRRC75B POM121L10P
nsv1057819	Chr.22:24290518 - 24624081 on Build GRCh38	Gain	GUCD1 ADORA2A-AS1 GGT1 SPECC1L SPECC1L-ADORA2A UPB1 ADORA2A SNRPD3 LRRC75B
esv2724041	Chr.22:23315914 - 24669376 on Build GRCh38	Deletion	CABIN1 GGT5 SPECC1L SPECC1L-ADORA2A IGLL1 MMP11 UPB1 MIF-AS1 SNRPD3 GSTTP1 LOC107985559 SUSD2 ZDHHC8P1 LOC107985555 BCRP3 LOC100652871 ZNF70 ADORA2A LRRC75B GUSBP11 LOC101929374 POM121L9P CHCHD10 BCR RGL4 LOC388882 SMARCB1 GSTT2 C22orf15 SLC2A11 POM121L10P VPREB3 DDT CES5AP1 DERL3 GUCD1 DDTL ADORA2A-AS1 GGT1 GSTT2B PCAT14 MIF DRICH1
nsv526567	Chr.22:23348138 - 24600663 on Build GRCh38	Gain	CABIN1 GGT5 SPECC1L SPECC1L-ADORA2A IGLL1 MMP11 UPB1 MIF-AS1 SNRPD3 GSTTP1 LOC107985559 SUSD2 ZDHHC8P1 LOC107985555 LOC100652871 ZNF70 ADORA2A LRRC75B GUSBP11 LOC101929374 POM121L9P CHCHD10 RGL4 LOC388882 SMARCB1 GSTT2 C22orf15 SLC2A11 VPREB3 DDT CES5AP1 DERL3 GUCD1 DDTL ADORA2A-AS1 GGT1 GSTT2B PCAT14 MIF DRICH1
nsv1055830	Chr.22:24005071 - 24643213 on Build GRCh38	Gain	POM121L9P CABIN1 GGT5 SPECC1L SPECC1L-ADORA2A UPB1 SNRPD3 GSTTP1 SUSD2 GUCD1 BCRP3 ADORA2A-AS1 GGT1 ADORA2A LRRC75B
esv3893463	Chr.22:24009046 - 24601506 on Build GRCh38	Gain	POM121L9P CABIN1 GGT5 SPECC1L SPECC1L-ADORA2A UPB1 SNRPD3 SUSD2 GUCD1 ADORA2A-AS1 GGT1 ADORA2A LRRC75B
dgv4528n100	Chr.22:23322244 - 24682765 on Build GRCh38	Gain	CABIN1 GGT5 SPECC1L SPECC1L-ADORA2A IGLL1 MMP11 UPB1 MIF-AS1 SNRPD3 GSTTP1 LOC107985559 SUSD2 ZDHHC8P1 LOC107985555 BCRP3 LOC100652871 ZNF70 ADORA2A LRRC75B GUSBP11 LOC101929374 POM121L9P CHCHD10 RGL4 LOC388882 SMARCB1 GSTT2 C22orf15 SLC2A11 POM121L10P VPREB3 DDT CES5AP1 DERL3 GUCD1 DDTL ADORA2A-AS1 GGT1 GSTT2B PCAT14 MIF DRICH1
nsv588744	Chr.22:24285587 - 24617379 on Build GRCh38	Gain	GUCD1 ADORA2A-AS1 GGT1 SPECC1L SPECC1L-ADORA2A UPB1 ADORA2A SNRPD3 LRRC75B
esv3575443	Chr.22:23348201 - 24670505 on Build GRCh38	Gain	CABIN1 GGT5 SPECC1L SPECC1L-ADORA2A IGLL1 MMP11 UPB1 MIF-AS1 SNRPD3 GSTTP1 LOC107985559 SUSD2 ZDHHC8P1 LOC107985555 BCRP3 LOC100652871 ZNF70 ADORA2A LRRC75B GUSBP11 LOC101929374 POM121L9P CHCHD10 RGL4 LOC388882 SMARCB1 GSTT2 C22orf15 SLC2A11 POM121L10P VPREB3 DDT CES5AP1 DERL3 GUCD1 DDTL ADORA2A-AS1 GGT1 GSTT2B PCAT14 MIF DRICH1
nsv9884	Chr.22:24415625 - 24662249 on Build GRCh38	Gain+Loss	GUCD1 BCRP3 ADORA2A-AS1 GGT1 SPECC1L SPECC1L-ADORA2A UPB1 ADORA2A SNRPD3 LRRC75B POM121L10P
nsv834160	Chr.22:24329972 - 24507687 on Build GRCh38	Gain	ADORA2A-AS1 SPECC1L SPECC1L-ADORA2A UPB1 ADORA2A

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

adenosine receptor signaling pathway
cAMP biosynthetic process
phagocytosis
apoptotic process
inflammatory response
cellular defense response
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
cell-cell signaling
central nervous system development
blood coagulation
sensory perception
blood circulation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
cellular protein metabolic process

Function(s)

G-protein coupled adenosine receptor activity
protein binding
enzyme binding
identical protein binding