Hs02327863_cn

• Gene Symbol: ADORA2A
• Assay Reference Genome Location: Chr.22:24432359 on build GRCh38
• Cytoband: 22q11.23

Target Gene Details

• Entrez Gene ID: 135
• Gene Name: adenosine A2a receptor
• Gene Aliases: A2aR, ADORA2, RDC8
• Location: Chr.22:24423597-24442360 on Build GRCh38
• Assay Gene Location: Overlaps Exon 3 - Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A	NM_000675.5			NP_000666.2
	NM_001278497.1			NP_001265426.1
	NM_001278498.1			NP_001265427.1
	NM_001278499.1			NP_001265428.1
	NM_001278500.1			NP_001265429.1
	NR_103543.1
	NR_103544.1
	AK123058.1
	AK289871.1
	AK301420.1
	AK312946.1
	BC013780.1			AAH13780.1
	DA270141.1
	DA781734.1
	DA942067.1
	DA983859.1
	EU036689.1	1	89
	EU036690.1
	EU036691.1
	EU036692.1
	EU036693.1
	EU036694.1
	HY102778.1

Target Gene Details

• Entrez Gene ID: 646023
• Gene Name: ADORA2A antisense RNA 1
• Gene Aliases: C22orf45
• Location: Chr.22:24429206-24495074 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A-AS1	NR_028484.2	5	909
	AK091970.1	1	72
	DB449907.2	5	635

Target Gene Details

• Entrez Gene ID: 101730217
• Gene Name: SPECC1L-ADORA2A readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.22:24270817-24442360 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPECC1L-ADORA2A	NR_103546.1
	AB209022.1			BAD92259.1
	GR939218.1
	GR939229.1
	GR939241.1
	GR939262.1
	GR939274.1
	GR939286.1
	GR939298.1
	GR939310.1
	GR939322.1
	GR939334.1
	GR939358.1
	GR939370.1
	GR939382.1
	GR939394.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2724068	Chr.22:24288741 - 24669870 on Build GRCh38	Deletion	SPECC1L-ADORA2A POM121L10P BCRP3 GUCD1 ADORA2A GGT1 ADORA2A-AS1 SPECC1L LRRC75B UPB1 SNRPD3
dgv8039n54	Chr.22:23323169 - 24601506 on Build GRCh38	Gain	LOC107985559 PCAT14 LOC100652871 RGL4 DDTL CES5AP1 DERL3 LRRC75B GGT5 SLC2A11 CHCHD10 GUCD1 ADORA2A CABIN1 SMARCB1 ZDHHC8P1 LOC101929374 C22orf15 UPB1 POM121L9P LOC107985555 ZNF70 GGT1 GSTT2 LOC388882 MMP11 GUSBP11 GSTT2B SPECC1L-ADORA2A MIF IGLL1 ADORA2A-AS1 VPREB3 DDT DRICH1 GSTTP1 SUSD2 SPECC1L SNRPD3 MIF-AS1
nsv1057819	Chr.22:24290518 - 24624081 on Build GRCh38	Gain	SPECC1L-ADORA2A GUCD1 ADORA2A GGT1 ADORA2A-AS1 SPECC1L LRRC75B UPB1 SNRPD3
nsv526567	Chr.22:23348138 - 24600663 on Build GRCh38	Gain	LOC107985559 PCAT14 LOC100652871 RGL4 DDTL CES5AP1 DERL3 LRRC75B GGT5 SLC2A11 CHCHD10 GUCD1 ADORA2A CABIN1 SMARCB1 ZDHHC8P1 LOC101929374 C22orf15 UPB1 POM121L9P LOC107985555 ZNF70 GGT1 GSTT2 LOC388882 MMP11 GUSBP11 GSTT2B SPECC1L-ADORA2A MIF IGLL1 ADORA2A-AS1 VPREB3 DDT DRICH1 GSTTP1 SUSD2 SPECC1L SNRPD3 MIF-AS1
esv2724041	Chr.22:23315914 - 24669376 on Build GRCh38	Deletion	LOC107985559 PCAT14 BCR LOC100652871 RGL4 DDTL CES5AP1 DERL3 LRRC75B GGT5 SLC2A11 POM121L10P CHCHD10 BCRP3 GUCD1 ADORA2A CABIN1 SMARCB1 ZDHHC8P1 LOC101929374 C22orf15 UPB1 POM121L9P LOC107985555 ZNF70 GGT1 GSTT2 LOC388882 MMP11 GUSBP11 GSTT2B SPECC1L-ADORA2A MIF IGLL1 ADORA2A-AS1 VPREB3 DDT DRICH1 GSTTP1 SUSD2 SPECC1L SNRPD3 MIF-AS1
nsv1055830	Chr.22:24005071 - 24643213 on Build GRCh38	Gain	GGT1 LRRC75B GGT5 SPECC1L-ADORA2A BCRP3 GUCD1 ADORA2A CABIN1 ADORA2A-AS1 GSTTP1 SUSD2 SPECC1L UPB1 POM121L9P SNRPD3
esv3893463	Chr.22:24009046 - 24601506 on Build GRCh38	Gain	GGT1 LRRC75B GGT5 SPECC1L-ADORA2A GUCD1 ADORA2A CABIN1 ADORA2A-AS1 SUSD2 SPECC1L UPB1 POM121L9P SNRPD3
dgv4528n100	Chr.22:23322244 - 24682765 on Build GRCh38	Gain	LOC107985559 PCAT14 LOC100652871 RGL4 DDTL CES5AP1 DERL3 LRRC75B GGT5 SLC2A11 POM121L10P CHCHD10 BCRP3 GUCD1 ADORA2A CABIN1 SMARCB1 ZDHHC8P1 LOC101929374 C22orf15 UPB1 POM121L9P LOC107985555 ZNF70 GGT1 GSTT2 LOC388882 MMP11 GUSBP11 GSTT2B SPECC1L-ADORA2A MIF IGLL1 ADORA2A-AS1 VPREB3 DDT DRICH1 GSTTP1 SUSD2 SPECC1L SNRPD3 MIF-AS1
nsv588744	Chr.22:24285587 - 24617379 on Build GRCh38	Gain	SPECC1L-ADORA2A GUCD1 ADORA2A GGT1 ADORA2A-AS1 SPECC1L LRRC75B UPB1 SNRPD3
nsv9884	Chr.22:24415625 - 24662249 on Build GRCh38	Gain+Loss	SPECC1L-ADORA2A POM121L10P BCRP3 GUCD1 ADORA2A GGT1 ADORA2A-AS1 SPECC1L LRRC75B UPB1 SNRPD3
esv3575443	Chr.22:23348201 - 24670505 on Build GRCh38	Gain	LOC107985559 PCAT14 LOC100652871 RGL4 DDTL CES5AP1 DERL3 LRRC75B GGT5 SLC2A11 POM121L10P CHCHD10 BCRP3 GUCD1 ADORA2A CABIN1 SMARCB1 ZDHHC8P1 LOC101929374 C22orf15 UPB1 POM121L9P LOC107985555 ZNF70 GGT1 GSTT2 LOC388882 MMP11 GUSBP11 GSTT2B SPECC1L-ADORA2A MIF IGLL1 ADORA2A-AS1 VPREB3 DDT DRICH1 GSTTP1 SUSD2 SPECC1L SNRPD3 MIF-AS1
nsv834160	Chr.22:24329972 - 24507687 on Build GRCh38	Gain	SPECC1L-ADORA2A ADORA2A ADORA2A-AS1 SPECC1L UPB1

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

adenosine receptor signaling pathway
cAMP biosynthetic process
phagocytosis
apoptotic process
inflammatory response
cellular defense response
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
cell-cell signaling
central nervous system development
blood coagulation
sensory perception
blood circulation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
cellular protein metabolic process

Function(s)

G-protein coupled adenosine receptor activity
protein binding
enzyme binding
identical protein binding