Hs02329683_cn

• Gene Symbol: POLR2I
• Assay Reference Genome Location: Chr.19:36114349 on build GRCh38
• Cytoband: 19q13.12

Target Gene Details

• Entrez Gene ID: 5438
• Gene Name: RNA polymerase II subunit I
• Gene Aliases: RPB9, hRPB14.5
• Location: Chr.19:36113709-36115304 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR2I	NM_006233.4			NP_006224.1
	AK312206.1
	BC017112.1			AAH17112.1
	BC067794.1			AAH67794.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833815	Chr.19:36028901 - 36134034 on Build GRCh38	Loss	WDR62 TBCB POLR2I LOC101927572 OVOL3 CLIP3 THAP8

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase, RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

mRNA splicing, via spliceosome
maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter
transcription-coupled nucleotide-excision repair
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
fibroblast growth factor receptor signaling pathway
gene expression
gene silencing by RNA
somatic stem cell population maintenance
snRNA transcription from RNA polymerase II promoter
positive regulation of viral transcription

Function(s)

nucleic acid binding
DNA-directed RNA polymerase activity
zinc ion binding