Hs02355624_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137307066 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Within Exon 32

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4	22	2711	NP_060290.3
	XM_011518810.1	24	3176	XP_011517112.1
	XM_011518814.1	16	2126	XP_011517116.1
	XM_011518815.1	13	1810	XP_011517117.1
	XM_017014861.1	25	3320	XP_016870350.1
	XM_017014862.1	23	3061	XP_016870351.1
	XM_017014863.1	23	3019	XP_016870352.1
	XM_017014864.1	22	3381	XP_016870353.1
	XM_017014865.1	22	3028	XP_016870354.1
	XM_017014866.1	21	2684	XP_016870355.1
	XM_017014867.1	21	2725	XP_016870356.1
	AB061798.1	15	2021	BAC10986.1
	AI682614.1	1	179
	AK055004.1	12	1843	BAB70838.1
	AK094438.1	22	2611	BAC04356.1
	BU947354.1	4	433

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	NDOR1 NRARP SLC34A3 TPRN FAM166A RNF224 TUBB4B TOR4A RNF208 CYSRT1 TMEM203 EXD3 STPG3 ANAPC2 NELFB C9orf173-AS1 SSNA1
dgv13011n54	Chr.9:137223996 - 137338927 on Build GRCh38	Loss	TUBB4B TOR4A CYSRT1 NRARP EXD3 SLC34A3 STPG3 NELFB C9orf173-AS1 FAM166A RNF224
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	PHPT1 CCDC183 C8G NRARP LOC101930307 FAM166A RNF224 TRAF2 FBXW5 EXD3 STPG3 LCNL1 MIR4292 ANAPC2 NELFB RABL6 SAPCD2 MAN1B1-AS1 MIR7114 TPRN EDF1 MAN1B1 C9orf139 MIR3621 GRIN1 LRRC26 MAMDC4 CYSRT1 TMEM203 UAP1L1 NSMF CCDC183-AS1 ENTPD8 SLC34A3 PRR31 ABCA2 MIR4479 TUBB4B TOR4A ENTPD2 PTGDS FUT7 C9orf173-AS1 CLIC3 NPDC1 NDOR1 C9orf172 PNPLA7 DPP7 NOXA1 RNF208 C9orf142 LCN12 TMEM210 SSNA1
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	NOXA1 ENTPD8 EXD3
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	NDOR1 NRARP SLC34A3 TPRN MIR3621 GRIN1 LRRC26 FAM166A RNF224 TUBB4B TOR4A RNF208 CYSRT1 TMEM203 EXD3 STPG3 ANAPC2 TMEM210 NELFB C9orf173-AS1 SSNA1
nsv8583	Chr.9:137303248 - 137322124 on Build GRCh38	Gain	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	NDOR1 ENTPD8 NRARP SLC34A3 TPRN MIR3621 GRIN1 LRRC26 FAM166A RNF224 TUBB4B NOXA1 TOR4A RNF208 CYSRT1 TMEM203 EXD3 STPG3 ANAPC2 TMEM210 NELFB C9orf173-AS1 SSNA1
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	PHPT1 CCDC183 C8G LCN10 NRARP LOC101930307 EGFL7 FAM166A RNF224 TRAF2 SNHG7 FAM69B FBXW5 EXD3 STPG3 LCNL1 MIR4292 ANAPC2 NELFB LCN6 RABL6 SAPCD2 MAN1B1-AS1 LCN15 TPRN EDF1 MAN1B1 C9orf139 MIR3621 GRIN1 LRRC26 MAMDC4 CYSRT1 TMEM203 UAP1L1 CCDC183-AS1 SLC34A3 PRR31 ABCA2 MIR6722 MIR4479 TUBB4B TOR4A ENTPD2 TMEM141 AGPAT2 PTGDS FUT7 C9orf173-AS1 CLIC3 NPDC1 NDOR1 LOC100128593 C9orf172 MIR126 SNORA17B DPP7 RNF208 SNORA17A C9orf142 LCN12 LINC01451 TMEM210 LCN8 HSPC324 SSNA1
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	TOR4A NRARP EXD3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding