Hs02359074_cn

• Gene Symbol: TRIM25
• Assay Reference Genome Location: Chr.17:56888427 on build GRCh38
• Cytoband: 17q22

Target Gene Details

• Entrez Gene ID: 7706
• Gene Name: tripartite motif containing 25
• Gene Aliases: EFP, RNF147, Z147, ZNF147
• Location: Chr.17:56887909-56914048 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRIM25	NM_005082.4	9	5226	NP_005073.2
	BX538220.1	1	2821

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv1004959	Chr.17:56888436 - 56888913 on Build GRCh38	Gain	TRIM25
esv32884	Chr.17:56683534 - 57002132 on Build GRCh38	Loss	SCPEP1 TRIM25 COIL MIR3614 DGKE C17orf67 MTVR2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein monoubiquitination
translesion synthesis
negative regulation of type I interferon production
ERAD pathway
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to estrogen
innate immune response
regulation of viral entry into host cell
negative regulation of viral entry into host cell
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
defense response to virus
interferon-gamma-mediated signaling pathway
cell-cell adhesion
regulation of viral release from host cell
negative regulation of viral release from host cell

Function(s)

transcription factor activity, sequence-specific DNA binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
acid-amino acid ligase activity
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion
ubiquitin protein ligase activity involved in ERAD pathway