Hs02359907_cn

• Gene Symbol: CREM
• Assay Reference Genome Location: Chr.10:35126980 on build GRCh38
• Cytoband: 10p11.21

Target Gene Details

• Entrez Gene ID: 1390
• Gene Name: cAMP responsive element modulator
• Gene Aliases: CREM-2, ICER, hCREM-2
• Location: Chr.10:35126841-35212958 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CREM	NM_001267562.1	1	140	NP_001254491.1
	NM_001267563.1	1	140	NP_001254492.1
	NM_001881.3	1	140	NP_001872.3
	NM_183013.2	1	140	NP_898831.1
	NR_051973.1	1	140
	NR_051974.1	1	140
	NR_051975.1	1	140
	XM_017015716.1	1	89	XP_016871205.1
	XM_017015717.1			XP_016871206.1
	XM_017015719.1			XP_016871208.1
	XM_017015723.1			XP_016871212.1
	XM_017015724.1	1	140	XP_016871213.1
	XM_017015727.1			XP_016871216.1
	XM_017015728.1	1	140	XP_016871217.1
	XM_017015729.1			XP_016871218.1
	XM_017015737.1			XP_016871226.1
	BC017117.1			AAH17117.1
	BC066342.1			AAH66342.1
	BG573680.1	1	109
	CB996061.1
	CN367927.1
	DA756152.1	1	140
	DR760671.1

Target Gene Details

• Entrez Gene ID: 8453
• Gene Name: cullin 2
• Gene Aliases: -
• Location: Chr.10:35008551-35126899 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CUL2	XM_011519745.1			XP_011518047.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1039051	Chr.10:35049745 - 35203997 on Build GRCh38	Gain	CUL2 MIR3611 CREM
dgv706n100	Chr.10:34881487 - 35230186 on Build GRCh38	Gain	CUL2 MIR3611 CREM
nsv550398	Chr.10:34885707 - 35271661 on Build GRCh38	Gain	CUL2 MIR3611 CREM CCNY
esv3576372	Chr.10:35088547 - 35160753 on Build GRCh38	Gain	CUL2 CREM

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

glucose metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
fatty acid metabolic process
glycosphingolipid metabolic process
signal transduction
multicellular organism development
spermatogenesis
cell differentiation
circadian regulation of gene expression
regulation of circadian rhythm
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
response to cAMP
G1/S transition of mitotic cell cycle
cell cycle arrest
negative regulation of cell proliferation
viral process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
regulation of transcription from RNA polymerase II promoter in response to hypoxia
intrinsic apoptotic signaling pathway

Function(s)

core promoter sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
cAMP response element binding protein binding
ubiquitin protein ligase binding
protein complex binding
ubiquitin protein ligase activity