Hs02388854_cn

• Gene Symbol: ARHGAP45
• Assay Reference Genome Location: Chr.19:1074180 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 23526
• Gene Name: Rho GTPase activating protein 45
• Gene Aliases: HA-1, HLA-HA1, HMHA1
• Location: Chr.19:1065923-1087831 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP45	NM_001258328.2	7	1018	NP_001245257.1
	NM_001282335.1	6	584	NP_001269264.1
	NM_001321232.1	7	954	NP_001308161.1
	NM_012292.4	7	1107	NP_036424.2
	XM_006722713.1	7	1107	XP_006722776.1
	XM_011527858.1	7	954	XP_011526160.1
	AK128097.1	6	584
	AK300341.1	7	1010
	AK304271.1	7	978
	AK304765.1	6	625
	BC035564.1	7	852	AAH35564.1
	BC065223.1	7	1099	AAH65223.1
	CN312499.1
	D86976.1	7	955

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1058677	Chr.19:1054061 - 1283189 on Build GRCh38	Loss	LOC102725180 CIRBP EFNA2 GPX4 CIRBP-AS1 ABCA7 C19orf24 ARHGAP45 POLR2E STK11 MIDN ATP5D CBARP SBNO2
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	LOC102725180 WDR18 CIRBP CNN2 KISS1R EFNA2 GPX4 TMEM259 CIRBP-AS1 RNU6-9 ABCA7 R3HDM4 C19orf24 ARHGAP45 GRIN3B LOC105372235 RNU6-2 POLR2E STK11 MIDN ATP5D ARID3A CBARP SBNO2
dgv136n111	Chr.19:1038223 - 1329640 on Build GRCh38	Deletion	LOC102725180 CIRBP CNN2 EFNA2 GPX4 CIRBP-AS1 ABCA7 C19orf24 ARHGAP45 POLR2E STK11 MIDN ATP5D CBARP SBNO2
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	CIRBP CNN2 KISS1R TMEM259 ABCA7 C19orf24 ARHGAP45 GRIN3B RNU6-2 CBARP SBNO2 LOC102725180 MED16 WDR18 EFNA2 GPX4 CIRBP-AS1 RNU6-9 R3HDM4 LOC105372235 POLR2E STK11 MIDN ATP5D ARID3A
nsv470102	Chr.19:1046521 - 1152656 on Build GRCh38	Loss	ARHGAP45 POLR2E GPX4 ABCA7 SBNO2
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	ARHGAP45 WDR18 GRIN3B LOC105372235 CNN2 RNU6-2 POLR2E ARID3A GPX4 TMEM259 ABCA7 SBNO2
nsv833704	Chr.19:951641 - 1144486 on Build GRCh38	Gain	ARHGAP45 WDR18 GRIN3B LOC105372235 CNN2 RNU6-2 POLR2E ARID3A GPX4 TMEM259 ABCA7 SBNO2
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	GZMM PRTN3 CFD CNN2 PRSS57 C2CD4C KISS1R FSTL3 TMEM259 TPGS1 ABCA7 SHC2 ARHGAP45 RNF126 CDC34 GRIN3B RNU6-2 HCN2 PLPPR3 MIR4745 ODF3L2 MISP PALM MED16 WDR18 THEG MIR3187 GPX4 RNU6-9 R3HDM4 POLRMT FGF22 AZU1 PTBP1 LOC105372235 MADCAM1 POLR2E ARID3A ELANE LOC101928450 BSG
dgv135n111	Chr.19:1014378 - 1156398 on Build GRCh38	Deletion	ARHGAP45 CNN2 RNU6-2 POLR2E GPX4 TMEM259 ABCA7 SBNO2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
metal ion binding