Hs02405486_cn

• Gene Symbol: UBB
• Assay Reference Genome Location: Chr.17:16381063 on build GRCh38
• Cytoband: 17p11.2

Target Gene Details

• Entrez Gene ID: 7314
• Gene Name: ubiquitin B
• Gene Aliases: HEL-S-50
• Location: Chr.17:16380793-16382745 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBB	NM_001281716.1			NP_001268645.1
	NM_001281720.1			NP_001268649.1
	NM_018955.3	1	267	NP_061828.1
	AK129498.1
	AK300882.1
	BC000379.2			AAH00379.1
	BC015127.1			AAH15127.1
	BC026301.1			AAH26301.1
	BC031027.1			AAH31027.1
	BC038999.1			AAH38999.1
	BC046123.2			AAH46123.1
	BP307496.1	1	267
	BU661443.1
	GQ472200.1
	HY014043.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063764	Chr.17:16268335 - 16759600 on Build GRCh38	Loss	ZNF624 UBB LRRC75A PIGL LRRC75A-AS1 MIR1288 ZNF287 SNORD65 SNORD49B CENPV TRPV2 SNORD49A CCDC144A
esv2715702	Chr.17:15750514 - 16668268 on Build GRCh38	Deletion	ZNF624 LOC101928567 UBB LRRC75A ADORA2B PIGL CDRT15P2 LRRC75A-AS1 MEIS3P1 MIR1288 ZNF287 SNORD65 NCOR1 TTC19 ZSWIM7 SNORD49B CENPV TRPV2 SNORD49A CCDC144A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
activation of MAPK activity
protein polyubiquitination
nucleotide-excision repair, DNA damage recognition
nucleotide-excision repair, DNA duplex unwinding
stimulatory C-type lectin receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
MyD88-independent toll-like receptor signaling pathway
glycogen biosynthetic process
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
transforming growth factor beta receptor signaling pathway
Notch signaling pathway
I-kappaB kinase/NF-kappaB signaling
JNK cascade
fibroblast growth factor receptor signaling pathway
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
Wnt signaling pathway
endosomal transport
macroautophagy
viral life cycle
virion assembly
translesion synthesis
negative regulation of transforming growth factor beta receptor signaling pathway
anaphase-promoting complex-dependent catabolic process
positive regulation of protein ubiquitination
regulation of type I interferon production
negative regulation of type I interferon production
tumor necrosis factor-mediated signaling pathway
nucleotide-excision repair, DNA incision
ion transmembrane transport
TRIF-dependent toll-like receptor signaling pathway
interstrand cross-link repair
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
ERBB2 signaling pathway
negative regulation of epidermal growth factor receptor signaling pathway
error-prone translesion synthesis
DNA damage response, detection of DNA damage
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
cellular protein metabolic process
innate immune response
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of transcription from RNA polymerase II promoter
mitochondrion transport along microtubule
neuron projection morphogenesis
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
stress-activated MAPK cascade
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of mitochondrial membrane potential
Wnt signaling pathway, planar cell polarity pathway
regulation of proteasomal protein catabolic process
regulation of transcription from RNA polymerase II promoter in response to hypoxia
nucleotide-binding oligomerization domain containing signaling pathway
global genome nucleotide-excision repair
error-free translesion synthesis
intracellular transport of virus
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
regulation of neuron death
regulation of signal transduction by p53 class mediator
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of protein monoubiquitination

Function(s)

protein binding