Hs02411523_cn

• Gene Symbol: DBNL
• Assay Reference Genome Location: Chr.7:44058965 on build GRCh38
• Cytoband: 7p13

Target Gene Details

• Entrez Gene ID: 28988
• Gene Name: drebrin like
• Gene Aliases: ABP1, HIP-55, HIP55, SH3P7
• Location: Chr.7:44044640-44061716 on Build GRCh38
• Assay Gene Location: Overlaps Exon 9 - Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DBNL	NM_001014436.2			NP_001014436.1
	NM_001122956.1			NP_001116428.1
	NM_001284313.1			NP_001271242.1
	NM_001284315.1			NP_001271244.1
	NM_014063.6			NP_054782.2
	XM_011515325.1			XP_011513627.1
	AB209486.1			BAD92723.1
	AF077353.1			AAF80228.1
	AF151364.1			AAG13120.1
	AF197060.1			AAF13701.1
	AF218020.3			AAG17262.2
	AF250287.1			AAF81273.1
	AK027367.1			BAB55065.1
	AK126142.1
	AK293151.1
	AK293279.1
	AK293340.1
	AK293698.1
	AK296778.1
	AK298102.1
	AK300630.1
	AK302037.1
	BC011677.2			AAH11677.1
	BC031687.1			AAH31687.1
	CR457167.1			CAG33448.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv8082	Chr.7:43956156 - 44207229 on Build GRCh38	Gain	MIR4649 RASA4CP DBNL POLD2 MYL7 PGAM2 GCK LINC00957 YKT6 POLM AEBP1 POLR2J4 MIR6838 SPDYE1 MIR6837
nsv428165	Chr.7:43855828 - 44172960 on Build GRCh38	Gain	MIR4649 RASA4CP DBNL MRPS24 POLD2 URGCP-MRPS24 MYL7 PGAM2 URGCP GCK LINC00957 POLM UBE2D4 AEBP1 POLR2J4 MIR6838 SPDYE1 LOC107986791 MIR6837
nsv470210	Chr.7:44045936 - 44139229 on Build GRCh38	Loss	MIR4649 POLM DBNL POLD2 AEBP1 MYL7 MIR6838 PGAM2 MIR6837
nsv830980	Chr.7:43865998 - 44078539 on Build GRCh38	Loss	RASA4CP DBNL MRPS24 URGCP-MRPS24 PGAM2 URGCP LINC00957 POLM UBE2D4 POLR2J4 MIR6838 SPDYE1 LOC107986791 MIR6837

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein, cytoskeletal protein, non-motor actin binding protein

Gene Ontology Categories:

Process(es)

adaptive immune response
receptor-mediated endocytosis
activation of JUN kinase activity
synapse assembly
Rac protein signal transduction
neuron projection morphogenesis
podosome assembly
ruffle assembly
cell-cell adhesion

Function(s)

actin binding
protein binding
protein C-terminus binding
enzyme activator activity
protein domain specific binding
actin filament binding
cadherin binding involved in cell-cell adhesion