Hs02412040_cn

• Gene Symbol: MXD4
• Assay Reference Genome Location: Chr.4:2249376 on build GRCh38
• Cytoband: 4p16.3

Target Gene Details

• Entrez Gene ID: 10608
• Gene Name: MAX dimerization protein 4
• Gene Aliases: MAD4, MST149, MSTP149, bHLHc12
• Location: Chr.4:2247432-2262143 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MXD4	NM_006454.2	6	1830	NP_006445.1
	XM_011513388.2	7	2335	XP_011511690.1
	AF082740.1	6	1830	AAF98553.1
	AK026392.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv508990	Chr.4:2246239 - 2324327 on Build GRCh38	Insertion	MIR4800 ZFYVE28 MXD4
nsv593376	Chr.4:2246106 - 2251118 on Build GRCh38	Loss	MIR4800 MXD4
nsv1009347	Chr.4:2200935 - 2516063 on Build GRCh38	Gain	MIR4800 RNF4 HAUS3 POLN ZFYVE28 CFAP99 MXD4
esv2726835	Chr.4:2019561 - 2959568 on Build GRCh38	Deletion	MIR4800 NAT8L MFSD10 CFAP99 C4orf48 FAM193A RNF4 HAUS3 POLN NOP14 ZFYVE28 TNIP2 NOP14-AS1 SH3BP2 ADD1 MXD4
nsv593375	Chr.4:2243138 - 2251253 on Build GRCh38	Loss	MIR4800 MXD4
dgv8910n54	Chr.4:2249015 - 2262496 on Build GRCh38	Loss	MIR4800 MXD4
nsv829838	Chr.4:2155167 - 2349950 on Build GRCh38	Loss	MIR4800 HAUS3 POLN ZFYVE28 MXD4

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of cell proliferation

Function(s)

DNA binding
transcription corepressor activity
protein binding
protein dimerization activity