Hs02430529_cn

• Gene Symbol: KANK2
• Assay Reference Genome Location: Chr.19:11165092 on build GRCh38
• Cytoband: 19p13.2

Target Gene Details

• Entrez Gene ID: 25959
• Gene Name: KN motif and ankyrin repeat domains 2
• Gene Aliases: ANKRD25, MXRA3, PPKWH, SIP
• Location: Chr.19:11164267-11197567 on Build GRCh38
• Assay Gene Location: Within Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KANK2	NM_001136191.2	13	4383	NP_001129663.1
	NM_015493.6	11	4125	NP_056308.3
	AB040951.2	12	4335
	AB284125.1	14	4566
	AL117489.1	1	1139	CAB55958.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1065030	Chr.19:11149372 - 11199804 on Build GRCh38	Gain	SPC24 DOCK6 KANK2

More Information

Additional Information:

For this assay, SNP(s) [rs75254697] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor actin binding protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
apoptotic process
negative regulation of cell proliferation
negative regulation of intracellular estrogen receptor signaling pathway
negative regulation of programmed cell death
negative regulation of vitamin D receptor signaling pathway
negative regulation of G1/S transition of mitotic cell cycle

Function(s)

protein binding