Hs02543278_cn

• Gene Symbol: PTGER4
• Assay Reference Genome Location: Chr.5:40693171 on build GRCh38
• Cytoband: 5p13.1

Target Gene Details

• Entrez Gene ID: 5734
• Gene Name: prostaglandin E receptor 4
• Gene Aliases: EP4, EP4R
• Location: Chr.5:40679930-40740932 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTGER4	NM_000958.2	3	2852	NP_000949.1
	XM_017009659.1			XP_016865148.1
	BQ029720.1
	CD000197.1	1	369

More Information

• Set Membership: Intragenic, Exonic, non-DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

negative regulation of peptide secretion
immune response
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
JNK cascade
female pregnancy
positive regulation of cell proliferation
response to mechanical stimulus
positive regulation of gene expression
negative regulation of hydrogen peroxide metabolic process
regulation of circadian sleep/wake cycle, wakefulness
positive regulation of smooth muscle cell migration
positive regulation of cAMP biosynthetic process
response to lipopolysaccharide
response to progesterone
positive regulation of interleukin-8 production
negative regulation of integrin activation
positive regulation of urine volume
positive regulation of renal sodium excretion
T-helper cell differentiation
negative regulation of circadian sleep/wake cycle, REM sleep
chemokinesis
response to drug
positive regulation of tyrosine phosphorylation of Stat3 protein
response to amino acid
positive regulation of osteoblast differentiation
positive regulation of bone resorption
positive regulation of cell adhesion
positive regulation of circadian sleep/wake cycle, non-REM sleep
negative regulation of cytokine secretion
negative regulation of interleukin-1 alpha secretion
positive regulation of cytokine secretion
negative regulation of inflammatory response
positive regulation of inflammatory response
regulation of stress fiber assembly
negative regulation of nitric-oxide synthase biosynthetic process
maternal process involved in parturition
bone development
positive regulation of mucus secretion
ERK1 and ERK2 cascade
cellular response to mechanical stimulus
cellular response to glucose stimulus
cellular response to interleukin-1
cellular response to prostaglandin E stimulus
positive regulation of wound healing
ductus arteriosus closure
positive regulation of hyaluronan biosynthetic process
response to salt
negative regulation of ductus arteriosus closure
negative regulation of small intestine smooth muscle contraction
positive regulation of calcitonin secretion
positive regulation of chemokinesis
positive regulation of matrix metallopeptidase secretion
negative regulation of tumor necrosis factor secretion
negative regulation of endothelin secretion
positive regulation of substance P secretion, neurotransmission
response to water-immersion restraint stress
positive regulation of antral ovarian follicle growth
positive regulation of neutrophil extravasation
negative regulation of eosinophil extravasation
positive regulation of interleukin-10 secretion

Function(s)

prostaglandin E receptor activity
protein binding