Hs02606464_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143992771 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1	7	1324	NP_000828.1
	NM_001009184.1	7	1212	NP_001009184.1
	AB097026.1	7	1136	BAC77379.1
	AK127640.1	7	1360
	AK294127.1	8	1069
	AL157442.1	1	55	CAB75662.3
	BC041788.1	7	1170	AAH41788.2
	BC084553.1	6	1061	AAH84553.1
	U44954.1	4	395	AAB94292.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	PARP10 PLEC GRINA
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	MFSD3 CYHR1 MAF1 WDR97 SCRT1 CPSF1 GPT HSF1 OPLAH SLC52A2 SPATC1 PARP10 HGH1 ADCK5 SCX TONSL-AS1 GPAA1 MIR7112 SMPD5 SHARPIN TMEM249 EXOSC4 BOP1 MIR661 PLEC MIR1234 TONSL MIR939 MIR6848 RECQL4 SLC39A4 MIR6893 MIR6849 MIR6846 CYC1 FOXH1 KIFC2 MROH1 FBXL6 LOC101928902 VPS28 LOC101928953 MIR6847 PPP1R16A GRINA DGAT1 LRRC14
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	MFSD3 CYHR1 MAF1 WDR97 SCRT1 CPSF1 GPT HSF1 OPLAH SLC52A2 SPATC1 PARP10 HGH1 ADCK5 SCX TONSL-AS1 GPAA1 MIR7112 SMPD5 SHARPIN TMEM249 EXOSC4 BOP1 MIR661 PLEC MIR1234 TONSL MIR939 MIR6848 RECQL4 SLC39A4 MIR6893 MIR6849 MIR6846 CYC1 FOXH1 KIFC2 MROH1 FBXL6 LOC101928902 VPS28 LOC101928953 MIR6847 PPP1R16A GRINA DGAT1 LRRC14
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	MAF1 WDR97 OPLAH SPATC1 PARP10 MIR6846 GPAA1 CYC1 SMPD5 SHARPIN EXOSC4 MIR6847 PLEC GRINA
dgv906n27	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	MAF1 WDR97 EPPK1 OPLAH SPATC1 PARP10 HGH1 MIR6846 GPAA1 CYC1 SMPD5 SHARPIN MROH1 EXOSC4 MIR6847 MIR661 PLEC GRINA
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	MAF1 WDR97 EPPK1 OPLAH SPATC1 PARP10 MIR6846 GPAA1 CYC1 SMPD5 SHARPIN EXOSC4 MIR6847 MIR661 PLEC GRINA
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	NRBP2 EPPK1 MIR937 OPLAH SPATC1 PARP10 MIR6845 MIR6846 SCRIB LOC642574 SMPD5 EXOSC4 PUF60 MIR6847 MIR661 PLEC GRINA
dgv12432n54	Chr.8:143902404 - 144007080 on Build GRCh38	Loss	PARP10 MIR661 PLEC GRINA
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	GPAA1 CYC1 SMPD5 EXOSC4 OPLAH SPATC1 PARP10 MIR6847 MIR661 MIR6846 PLEC GRINA
nsv612907	Chr.8:143917935 - 144097007 on Build GRCh38	Gain+Loss	GPAA1 CYC1 SMPD5 EXOSC4 OPLAH SPATC1 PARP10 MIR6847 MIR661 MIR6846 PLEC GRINA

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding