Hs02645189_cn

• Gene Symbol: TOB2
• Assay Reference Genome Location: Chr.22:41437366 on build GRCh38
• Cytoband: 22q13.2

Target Gene Details

• Entrez Gene ID: 10766
• Gene Name: transducer of ERBB2, 2
• Gene Aliases: APRO5, TOB4, TOBL, TROB2
• Location: Chr.22:41433488-41448230 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TOB2	NM_016272.3			NP_057356.1
	XM_005261315.2			XP_005261372.1
	XM_006724105.3			XP_006724168.1
	XM_017028539.1			XP_016884028.1
	AB035207.1	1	194	BAA87042.1
	AB051450.1
	BC028919.1			AAH28919.1
	BC038957.1			AAH38957.1
	BM453650.1
	CR456594.1			CAG30480.1
	CR541684.1			CAG46485.1
	D64109.1	1	73	BAA10971.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834207	Chr.22:41282650 - 41463790 on Build GRCh38	Loss	TOB2 TEF ZC3H7B PHF5A RANGAP1 LOC100996598
nsv516925	Chr.22:41252498 - 41585953 on Build GRCh38	Loss	ACO2 TOB2 TEF CSDC2 POLR3H ZC3H7B LOC105373044 PHF5A MIR6889 PMM1 RANGAP1 LOC100996598
nsv834208	Chr.22:41363612 - 41554028 on Build GRCh38	Loss	ACO2 TOB2 TEF POLR3H LOC105373044 PHF5A LOC100996598
nsv589050	Chr.22:41231539 - 41454496 on Build GRCh38	Gain	TOB2 TEF ZC3H7B MIR6889 CHADL RANGAP1 LOC100996598
nsv524585	Chr.22:40993505 - 41794305 on Build GRCh38	Loss	SNORD140 EP300 L3MBTL2 POLR3H LOC105373044 PHF5A MIR6889 CHADL PMM1 RANGAP1 LOC100996598 DESI1 SNU13 ACO2 EP300-AS1 TOB2 TEF MEI1 CSDC2 ZC3H7B XRCC6 C22orf46 MIR1281

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

female gamete generation
negative regulation of cell proliferation
regulation of gene expression
negative regulation of osteoclast differentiation
positive regulation of ossification

Function(s)

protein binding
vitamin D receptor binding