Hs02688105_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137188629 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1

Target Gene Details

• Entrez Gene ID: 8636
• Gene Name: SS nuclear autoantigen 1
• Gene Aliases: N14, NA-14, NA14
• Location: Chr.9:137188602-137190370 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SSNA1	NM_003731.2			NP_003722.2
	BC000864.1			AAH00864.1
	DB466912.1
	Z96932.1			CAB09660.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	LOC101930307 UAP1L1 TPRN RNF208 MAN1B1-AS1 LRRC26 TMEM210 GRIN1 NDOR1 CYSRT1 TMEM203 SSNA1 DPP7 RNF224 MIR3621 MAN1B1 ANAPC2 SLC34A3
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	C9orf173-AS1 FAM166A TPRN STPG3 RNF208 NRARP NELFB EXD3 TUBB4B NDOR1 CYSRT1 TMEM203 SSNA1 TOR4A RNF224 ANAPC2 SLC34A3
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	NOXA1 LOC101930307 TPRN SAPCD2 NELFB TUBB4B C9orf139 RABL6 PTGDS NDOR1 FUT7 MIR3621 MAN1B1 ANAPC2 PNPLA7 SLC34A3 STPG3 ENTPD2 CCDC183-AS1 C9orf142 PRR31 EDF1 MAN1B1-AS1 EXD3 GRIN1 TRAF2 MIR4292 ENTPD8 TMEM203 SSNA1 PHPT1 DPP7 MIR4479 ABCA2 C9orf173-AS1 FAM166A NRARP MAMDC4 FBXW5 CYSRT1 LCN12 TOR4A CCDC183 RNF224 UAP1L1 RNF208 MIR7114 NSMF LRRC26 TMEM210 C9orf172 CLIC3 LCNL1 NPDC1 C8G
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	C9orf173-AS1 FAM166A TPRN STPG3 RNF208 NRARP NELFB LRRC26 EXD3 TMEM210 TUBB4B GRIN1 NDOR1 CYSRT1 TMEM203 SSNA1 TOR4A RNF224 MIR3621 ANAPC2 SLC34A3
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	LOC101930307 UAP1L1 ENTPD2 MAN1B1-AS1 SAPCD2 LRRC26 TMEM210 C9orf139 GRIN1 NPDC1 SSNA1 DPP7 FUT7 MIR3621 MAN1B1 ANAPC2
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	NOXA1 C9orf173-AS1 FAM166A TPRN STPG3 RNF208 NRARP NELFB LRRC26 EXD3 TMEM210 TUBB4B GRIN1 NDOR1 ENTPD8 CYSRT1 TMEM203 SSNA1 TOR4A RNF224 MIR3621 ANAPC2 SLC34A3
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	LOC101930307 TPRN MIR6722 SAPCD2 NELFB TUBB4B C9orf139 RABL6 PTGDS NDOR1 LCN8 FUT7 MIR3621 MAN1B1 ANAPC2 SLC34A3 LOC100128593 STPG3 MIR126 ENTPD2 FAM69B CCDC183-AS1 C9orf142 PRR31 EDF1 MAN1B1-AS1 EXD3 AGPAT2 GRIN1 TRAF2 MIR4292 LCN6 TMEM203 SSNA1 PHPT1 DPP7 MIR4479 ABCA2 C9orf173-AS1 FAM166A EGFL7 NRARP TMEM141 LCN15 SNORA17B MAMDC4 FBXW5 CYSRT1 LCN12 TOR4A CCDC183 RNF224 HSPC324 LCN10 UAP1L1 RNF208 LRRC26 SNORA17A SNHG7 TMEM210 C9orf172 LINC01451 CLIC3 LCNL1 NPDC1 C8G

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation
G2/M transition of mitotic cell cycle
intraciliary transport
ciliary receptor clustering involved in smoothened signaling pathway

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity
protein binding
identical protein binding