Hs02694840_cn

• Gene Symbol: TOB2
• Assay Reference Genome Location: Chr.22:41435078 on build GRCh38
• Cytoband: 22q13.2

Target Gene Details

• Entrez Gene ID: 10766
• Gene Name: transducer of ERBB2, 2
• Gene Aliases: APRO5, TOB4, TOBL, TROB2
• Location: Chr.22:41433488-41448230 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TOB2	NM_016272.3	2	2975	NP_057356.1
	XM_005261315.2	2	4186	XP_005261372.1
	XM_006724105.3	2	3492	XP_006724168.1
	XM_017028539.1	2	5268	XP_016884028.1
	AB051450.1	2	2734
	BC038957.1	2	2748	AAH38957.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834207	Chr.22:41282650 - 41463790 on Build GRCh38	Loss	LOC100996598 PHF5A TEF ZC3H7B TOB2 RANGAP1
nsv516925	Chr.22:41252498 - 41585953 on Build GRCh38	Loss	LOC100996598 ACO2 LOC105373044 POLR3H PHF5A CSDC2 TEF PMM1 ZC3H7B TOB2 RANGAP1 MIR6889
nsv834208	Chr.22:41363612 - 41554028 on Build GRCh38	Loss	LOC100996598 ACO2 LOC105373044 POLR3H PHF5A TEF TOB2
nsv962798	Chr.22:41433542 - 41435164 on Build GRCh38	Duplication	TOB2
nsv589050	Chr.22:41231539 - 41454496 on Build GRCh38	Gain	LOC100996598 CHADL TEF ZC3H7B TOB2 RANGAP1 MIR6889
nsv524585	Chr.22:40993505 - 41794305 on Build GRCh38	Loss	MIR1281 XRCC6 LOC105373044 SNU13 TEF PMM1 L3MBTL2 ZC3H7B TOB2 SNORD140 MIR6889 EP300-AS1 LOC100996598 ACO2 C22orf46 POLR3H PHF5A CSDC2 CHADL MEI1 DESI1 RANGAP1 EP300

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

female gamete generation
negative regulation of cell proliferation
regulation of gene expression
negative regulation of osteoclast differentiation
positive regulation of ossification

Function(s)

protein binding
vitamin D receptor binding