Hs02741218_cn

• Gene Symbol: AGR2
• Assay Reference Genome Location: Chr.7:16792538 on build GRCh38
• Cytoband: 7p21.1

Target Gene Details

• Entrez Gene ID: 10551
• Gene Name: anterior gradient 2, protein disulphide isomerase family member
• Gene Aliases: AG2, GOB-4, HAG-2, HEL-S-116, PDIA17, XAG-2
• Location: Chr.7:16791811-16805114 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AGR2	XM_005249581.4	8	1054	XP_005249638.1
	AF038451.1	8	956	AAC82614.1
	AF038452.1	1	113
	AF115926.1	8	955	AAL54870.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv6289n100	Chr.7:16230707 - 17452994 on Build GRCh38	Gain	LRRC72 TSPAN13 SOSTDC1 AGR2 AHR AGR3 ISPD-AS1 ISPD LOC105375172 ANKMY2 BZW2 KCCAT333
nsv1028125	Chr.7:16489535 - 16807601 on Build GRCh38	Gain	LRRC72 TSPAN13 SOSTDC1 AGR2 ANKMY2 BZW2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

reductase

Gene Ontology Categories:

Process(es)

positive regulation of gene expression
positive regulation of cell-substrate adhesion
response to endoplasmic reticulum stress
positive regulation of epidermal growth factor receptor signaling pathway
digestive tract morphogenesis
positive regulation of developmental growth
lung goblet cell differentiation
negative regulation of cell death
mucus secretion
positive regulation of establishment of protein localization to plasma membrane
positive regulation of IRE1-mediated unfolded protein response
positive regulation of PERK-mediated unfolded protein response

Function(s)

dystroglycan binding
epidermal growth factor receptor binding
protein binding
protein homodimerization activity