Hs02764213_cn

• Gene Symbol: ARHGAP45
• Assay Reference Genome Location: Chr.19:1077848 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 23526
• Gene Name: Rho GTPase activating protein 45
• Gene Aliases: HA-1, HLA-HA1, HMHA1
• Location: Chr.19:1065923-1087831 on Build GRCh38
• Assay Gene Location: Within Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP45	NM_001258328.2			NP_001245257.1
	NM_001282334.1	1	1215	NP_001269263.1
	NM_001282335.1			NP_001269264.1
	NM_001321232.1			NP_001308161.1
	NM_012292.4			NP_036424.2
	XM_006722713.1			XP_006722776.1
	XM_011527858.1			XP_011526160.1
	XM_011527860.2			XP_011526162.1
	AK122776.1	1	406
	AK128097.1
	AK300341.1
	AK304271.1
	AK304765.1
	BC035564.1			AAH35564.1
	BC065223.1			AAH65223.1
	D86976.1
	DB157802.1	1	286

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1058677	Chr.19:1054061 - 1283189 on Build GRCh38	Loss	EFNA2 STK11 GPX4 LOC102725180 ABCA7 MIDN POLR2E CIRBP SBNO2 ATP5D CBARP CIRBP-AS1 C19orf24 ARHGAP45
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	GRIN3B EFNA2 RNU6-9 STK11 ARID3A GPX4 TMEM259 WDR18 LOC102725180 ABCA7 MIDN POLR2E CIRBP KISS1R LOC105372235 SBNO2 ATP5D CBARP CIRBP-AS1 RNU6-2 R3HDM4 CNN2 C19orf24 ARHGAP45
dgv136n111	Chr.19:1038223 - 1329640 on Build GRCh38	Deletion	EFNA2 STK11 GPX4 LOC102725180 ABCA7 MIDN POLR2E CIRBP SBNO2 ATP5D CBARP CIRBP-AS1 CNN2 C19orf24 ARHGAP45
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	EFNA2 STK11 TMEM259 ABCA7 POLR2E KISS1R SBNO2 ATP5D CBARP CIRBP-AS1 RNU6-2 R3HDM4 CNN2 GRIN3B RNU6-9 ARID3A GPX4 WDR18 LOC102725180 MIDN MED16 CIRBP LOC105372235 C19orf24 ARHGAP45
nsv470102	Chr.19:1046521 - 1152656 on Build GRCh38	Loss	SBNO2 GPX4 ABCA7 POLR2E ARHGAP45
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	GRIN3B LOC105372235 SBNO2 ARID3A GPX4 TMEM259 RNU6-2 WDR18 ABCA7 CNN2 POLR2E ARHGAP45
nsv833704	Chr.19:951641 - 1144486 on Build GRCh38	Gain	GRIN3B LOC105372235 SBNO2 ARID3A GPX4 TMEM259 RNU6-2 WDR18 ABCA7 CNN2 POLR2E ARHGAP45
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	FGF22 CFD ELANE MIR4745 POLRMT TMEM259 GZMM ABCA7 POLR2E KISS1R PALM HCN2 MISP RNU6-2 R3HDM4 MIR3187 CNN2 PRTN3 CDC34 THEG GRIN3B MADCAM1 TPGS1 RNU6-9 ARID3A GPX4 WDR18 MED16 BSG PRSS57 ODF3L2 LOC105372235 C2CD4C PTBP1 FSTL3 SHC2 RNF126 LOC101928450 PLPPR3 AZU1 ARHGAP45
dgv135n111	Chr.19:1014378 - 1156398 on Build GRCh38	Deletion	SBNO2 GPX4 TMEM259 RNU6-2 ABCA7 CNN2 POLR2E ARHGAP45

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
metal ion binding