Hs02779223_cn

• Gene Symbol: PPA2
• Assay Reference Genome Location: Chr.4:105399115 on build GRCh38
• Cytoband: 4q24

Target Gene Details

• Entrez Gene ID: 27068
• Gene Name: pyrophosphatase (inorganic) 2
• Gene Aliases: HSPC124, SID6-306
• Location: Chr.4:105369077-105474070 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPA2	NM_006903.4	7	638	NP_008834.3
	NM_176866.2	4	419	NP_789842.2
	NM_176867.3	2	227	NP_789843.2
	NM_176869.2	8	725	NP_789845.1
	AB026722.1	7	632	BAA84701.1
	AF161473.1	9	714	AAF29088.1
	AF217187.1	8	719	AAG36781.1
	AK000466.1	8	717	BAA91184.1
	AK289607.1	7	616
	AK299125.1	8	714
	AL136655.1	9	697	CAB66590.2
	AW953776.1
	BC022803.1	2	203	AAH22803.1
	BC039462.1	4	366	AAH39462.2
	BC057219.1	7	631	AAH57219.1
	CN423093.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1000196	Chr.4:103475625 - 106148054 on Build GRCh38	Loss	LOC101929529 TACR3 TET2 INTS12 TBCK LOC101929577 NPNT TET2-AS1 CXXC4 ARHGEF38 LOC101929468 PPA2 GSTCD ARHGEF38-IT1
nsv470063	Chr.4:104948391 - 105445052 on Build GRCh38	Loss	TET2-AS1 PPA2 TET2
nsv830027	Chr.4:105300853 - 105485581 on Build GRCh38	Gain	TET2-AS1 PPA2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

pyrophosphatase

Gene Ontology Categories:

Process(es)

tRNA aminoacylation for protein translation
protein dephosphorylation
diphosphate metabolic process

Function(s)

magnesium ion binding
inorganic diphosphatase activity
protein serine/threonine phosphatase activity