Hs02872637_cn

• Gene Symbol: CDH15
• Assay Reference Genome Location: Chr.16:89192316 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 1013
• Gene Name: cadherin 15
• Gene Aliases: CDH14, CDH3, CDHM, MCAD, MRD3
• Location: Chr.16:89171755-89195492 on Build GRCh38
• Assay Gene Location: Within Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDH15	NM_004933.2	11	1804	NP_004924.1
	BC008951.2	11	1779	AAH08951.1
	D83542.1	11	1804	BAA12012.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952072	Chr.16:89032193 - 89201992 on Build GRCh38	Deletion	CDH15 LOC400558 LINC00304 SLC22A31 ACSF3
nsv509638	Chr.16:89152681 - 89296203 on Build GRCh38	Insertion	CDH15 LOC400558 ZNF778 LINC00304 SLC22A31 ACSF3 LOC105371414 ANKRD11
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	APRT CDH15 LOC339059 LOC101927793 MIR4722 CTU2 GALNS PIEZO1 TRAPPC2L LOC400558 ZNF778 LINC00304 SLC22A31 LOC107987238 PABPN1L CDT1 LOC100289580 CBFA2T3 ACSF3 LOC105371409 LOC100129697
nsv573727	Chr.16:89169527 - 89193067 on Build GRCh38	Loss	CDH15
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	APRT CDH15 LOC101927793 GALNS TRAPPC2L LOC400558 LINC00304 SLC22A31 LOC107987238 PABPN1L CDT1 CBFA2T3 ACSF3 LOC105371409 LOC100129697
nsv457621	Chr.16:89100686 - 89217401 on Build GRCh38	Loss	CDH15 LOC400558 ZNF778 LINC00304 SLC22A31 ACSF3
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	APRT CDH15 LOC339059 LOC101927793 GALNS PIEZO1 LOC100287036 TRAPPC2L LOC400558 ZNF778 LINC00304 SLC22A31 LOC107987238 PABPN1L CDT1 LOC100289580 CBFA2T3 ACSF3 LOC105371409 LOC105371414 ANKRD11 LOC100129697
nsv573729	Chr.16:89189723 - 89193067 on Build GRCh38	Loss	CDH15
dgv3066n100	Chr.16:89067685 - 89301626 on Build GRCh38	Gain	CDH15 LOC400558 ZNF778 LINC00304 SLC22A31 ACSF3 LOC105371414 ANKRD11
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	TUBB8P7 VPS9D1 URAHP MIR4722 SNAI3 DEF8 TCF25 LINC00304 PABPN1L CDT1 CHMP1A APRT ZNF276 FAM157C CENPBD1 LOC107984817 CTU2 MC1R AFG3L1P PIEZO1 LOC100287036 TRAPPC2L LOC400558 ZNF778 CDK10 SLC22A31 CBFA2T3 ACSF3 ANKRD11 VPS9D1-AS1 DPEP1 CDH15 GAS8 LOC339059 MVD IL17C GALNS RPL13 SPIRE2 LOC107987238 FANCA SPATA33 LOC105371409 TUBB3 LOC100129697 SPG7 RNF166 DBNDD1 LOC101927793 LOC105371419 PRDM7 CPNE7 SNAI3-AS1 LOC101927817 SPATA2L LOC100289580 GAS8-AS1 CYBA LOC105371414 SNORD68
dgv5320n54	Chr.16:89114475 - 89197443 on Build GRCh38	Loss	CDH15 LOC400558 LINC00304 SLC22A31 ACSF3
nsv573728	Chr.16:89179547 - 89193067 on Build GRCh38	Gain+Loss	CDH15

More Information

Additional Information:

For this assay, SNP(s) [rs75791347] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

cadherin

Gene Ontology Categories:

Process(es)

cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
adherens junction organization
positive regulation of muscle cell differentiation

Function(s)

calcium ion binding
protein binding