Hs02876394_cn

• Gene Symbol: PTGDS
• Assay Reference Genome Location: Chr.9:136979191 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 5730
• Gene Name: prostaglandin D2 synthase
• Gene Aliases: L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2
• Location: Chr.9:136977504-136981742 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTGDS	NM_000954.5			NP_000945.3
	AA621632.1
	AK075333.1
	AK312817.1
	AY026356.1			AAK07679.1
	BC005939.1			AAH05939.1
	BG037037.1
	BM686612.1
	BT019921.1			AAV38724.1
	BT019922.1			AAV38725.1
	M61900.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13008n54	Chr.9:136977199 - 136980285 on Build GRCh38	Loss	PTGDS
dgv13007n54	Chr.9:136966179 - 137173890 on Build GRCh38	Loss	LOC101930307 GRIN1 PTGDS PRR31 CLIC3 C9orf139 LRRC26 UAP1L1 TMEM210 MAN1B1-AS1 ABCA2 C9orf142 LCNL1 NPDC1 MAN1B1 SAPCD2 MIR3621 ENTPD2 FUT7 DPP7
nsv615991	Chr.9:136972675 - 137011907 on Build GRCh38	Loss	PTGDS PRR31 CLIC3 ABCA2 C9orf142 LCNL1
nsv615992	Chr.9:136975638 - 136980181 on Build GRCh38	Loss	PTGDS
nsv818738	Chr.9:136740043 - 137009585 on Build GRCh38	Gain	PHPT1 PTGDS PRR31 CLIC3 TRAF2 LCN15 C9orf172 LCNL1 CCDC183 LOC100128593 C8G LCN10 MAMDC4 RABL6 ABCA2 C9orf142 CCDC183-AS1 LCN8 MIR6722 EDF1 TMEM141 LCN6 LCN12 MIR4292 FBXW5 MIR4479
nsv615994	Chr.9:136975930 - 136979942 on Build GRCh38	Gain	PTGDS
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	GRIN1 EXD3 PRR31 FAM166A CLIC3 TRAF2 C9orf172 LCNL1 TMEM203 CCDC183 NPDC1 PNPLA7 NELFB SLC34A3 ANAPC2 MAMDC4 NOXA1 RABL6 C9orf139 MIR7114 NRARP CYSRT1 C9orf173-AS1 MIR4292 MIR4479 NSMF PHPT1 RNF208 LOC101930307 PTGDS TUBB4B LRRC26 UAP1L1 SSNA1 SAPCD2 ENTPD2 NDOR1 FUT7 C8G DPP7 STPG3 TMEM210 MAN1B1-AS1 ABCA2 C9orf142 ENTPD8 MAN1B1 CCDC183-AS1 RNF224 EDF1 MIR3621 TPRN LCN12 FBXW5 TOR4A
nsv951206	Chr.9:136944849 - 137114548 on Build GRCh38	Deletion	LOC101930307 PTGDS PRR31 CLIC3 C9orf139 UAP1L1 MAN1B1-AS1 ABCA2 C9orf142 LCNL1 NPDC1 MAN1B1 SAPCD2 ENTPD2 FUT7 LCN12 C8G DPP7
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	GRIN1 NALT1 PRR31 CLIC3 TRAF2 LCN15 C9orf172 LCNL1 HSPC324 CCDC183 NPDC1 LOC100128593 SEC16A LCN10 DNLZ MAMDC4 AGPAT2 FAM69B RABL6 C9orf139 SNAPC4 NOTCH1 LCN8 MIR6722 SNORA17B MIR4292 MIR4479 INPP5E PHPT1 PMPCA MIR4673 LOC101930307 PTGDS LRRC26 UAP1L1 C9orf163 SAPCD2 EGFL7 ENTPD2 FUT7 MIR126 C8G DPP7 SDCCAG3 SNHG7 LINC01451 TMEM210 MAN1B1-AS1 ABCA2 C9orf142 MAN1B1 CARD9 CCDC183-AS1 EDF1 SNORA17A MIR3621 TMEM141 LCN6 LCN12 FBXW5 MIR4674
nsv616002	Chr.9:136977855 - 136981118 on Build GRCh38	Loss	PTGDS
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	GRIN1 EXD3 PRR31 FAM166A CLIC3 TRAF2 LCN15 C9orf172 LCNL1 TMEM203 HSPC324 CCDC183 NPDC1 LOC100128593 NELFB SLC34A3 LCN10 ANAPC2 MAMDC4 AGPAT2 FAM69B RABL6 C9orf139 NRARP LCN8 MIR6722 SNORA17B CYSRT1 C9orf173-AS1 MIR4292 MIR4479 PHPT1 RNF208 LOC101930307 PTGDS TUBB4B LRRC26 UAP1L1 SSNA1 SAPCD2 EGFL7 ENTPD2 NDOR1 FUT7 MIR126 C8G DPP7 STPG3 SNHG7 LINC01451 TMEM210 MAN1B1-AS1 ABCA2 C9orf142 MAN1B1 CCDC183-AS1 RNF224 EDF1 SNORA17A MIR3621 TMEM141 TPRN LCN6 LCN12 FBXW5 TOR4A

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transfer/carrier protein

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
transport
cyclooxygenase pathway
regulation of circadian sleep/wake cycle, sleep
response to glucocorticoid
negative regulation of male germ cell proliferation

Function(s)

prostaglandin-D synthase activity
transporter activity
retinoid binding
fatty acid binding
protein binding
small molecule binding