Hs02876394_cn

• Gene Symbol: PTGDS
• Assay Reference Genome Location: Chr.9:136979191 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 5730
• Gene Name: prostaglandin D2 synthase
• Gene Aliases: L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2
• Location: Chr.9:136977504-136981742 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTGDS	NM_000954.5			NP_000945.3
	AA621632.1
	AK075333.1
	AK312817.1
	AY026356.1			AAK07679.1
	BC005939.1			AAH05939.1
	BG037037.1
	BM686612.1
	BT019921.1			AAV38724.1
	BT019922.1			AAV38725.1
	M61900.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv615997	Chr.9:136977199 - 136984376 on Build GRCh38	Loss	LCNL1 PTGDS
nsv615991	Chr.9:136972675 - 137011907 on Build GRCh38	Loss	PRR31 CLIC3 LCNL1 ABCA2 C9orf142 PTGDS
dgv13007n54	Chr.9:136966179 - 137173890 on Build GRCh38	Loss	PRR31 GRIN1 CLIC3 TMEM210 SAPCD2 LCNL1 UAP1L1 C9orf139 ENTPD2 MAN1B1 PTGDS DPP7 FUT7 LRRC26 NPDC1 MIR3621 LOC101930307 MAN1B1-AS1 ABCA2 C9orf142
nsv615993	Chr.9:136975638 - 136983246 on Build GRCh38	Gain	LCNL1 PTGDS
nsv818738	Chr.9:136740043 - 137009585 on Build GRCh38	Gain	FBXW5 CLIC3 LCN8 LCNL1 LCN10 RABL6 LCN12 TRAF2 C8G ABCA2 MAMDC4 PRR31 MIR4292 TMEM141 CCDC183 LOC100128593 C9orf172 EDF1 LCN6 LCN15 PTGDS MIR6722 MIR4479 PHPT1 C9orf142 CCDC183-AS1
nsv615994	Chr.9:136975930 - 136979942 on Build GRCh38	Gain	PTGDS
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	GRIN1 ENTPD8 LCNL1 NDOR1 UAP1L1 LCN12 NOXA1 RNF208 SSNA1 TRAF2 LOC101930307 MAMDC4 PNPLA7 PRR31 TMEM210 NRARP MIR4292 NSMF CCDC183 ENTPD2 MAN1B1 EDF1 PTGDS NELFB MIR4479 TOR4A NPDC1 C9orf142 CCDC183-AS1 FBXW5 CLIC3 SAPCD2 TMEM203 SLC34A3 ANAPC2 RABL6 C9orf139 FUT7 FAM166A C8G MIR3621 C9orf173-AS1 ABCA2 TUBB4B STPG3 CYSRT1 C9orf172 EXD3 TPRN DPP7 MIR7114 LRRC26 PHPT1 MAN1B1-AS1 RNF224
nsv951206	Chr.9:136944849 - 137114548 on Build GRCh38	Deletion	PRR31 CLIC3 SAPCD2 LCNL1 UAP1L1 C9orf139 ENTPD2 LCN12 MAN1B1 PTGDS DPP7 FUT7 C8G NPDC1 LOC101930307 MAN1B1-AS1 ABCA2 C9orf142
nsv616002	Chr.9:136977855 - 136981118 on Build GRCh38	Loss	PTGDS
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	GRIN1 PMPCA LCN8 LCNL1 EGFL7 UAP1L1 LCN12 TRAF2 LOC101930307 MAMDC4 PRR31 TMEM210 MIR126 HSPC324 INPP5E MIR4292 CARD9 CCDC183 LOC100128593 ENTPD2 MAN1B1 EDF1 PTGDS C9orf163 MIR6722 MIR4479 FAM69B NPDC1 NOTCH1 SNHG7 C9orf142 CCDC183-AS1 FBXW5 CLIC3 SAPCD2 LCN10 RABL6 SEC16A C9orf139 NALT1 MIR4673 FUT7 SNAPC4 C8G MIR3621 ABCA2 TMEM141 DNLZ SNORA17A C9orf172 LCN6 LCN15 DPP7 LINC01451 SDCCAG3 LRRC26 PHPT1 SNORA17B MAN1B1-AS1 MIR4674 AGPAT2
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	GRIN1 LCN8 LCNL1 EGFL7 NDOR1 UAP1L1 LCN12 RNF208 SSNA1 TRAF2 LOC101930307 MAMDC4 PRR31 TMEM210 MIR126 HSPC324 NRARP MIR4292 CCDC183 LOC100128593 ENTPD2 MAN1B1 EDF1 PTGDS NELFB MIR6722 MIR4479 FAM69B TOR4A NPDC1 SNHG7 C9orf142 CCDC183-AS1 FBXW5 CLIC3 SAPCD2 TMEM203 SLC34A3 LCN10 ANAPC2 RABL6 C9orf139 FUT7 FAM166A C8G MIR3621 C9orf173-AS1 ABCA2 TUBB4B STPG3 TMEM141 CYSRT1 SNORA17A C9orf172 LCN6 LCN15 EXD3 TPRN DPP7 LINC01451 LRRC26 PHPT1 SNORA17B MAN1B1-AS1 RNF224 AGPAT2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transfer/carrier protein

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
transport
cyclooxygenase pathway
regulation of circadian sleep/wake cycle, sleep
response to glucocorticoid
negative regulation of male germ cell proliferation

Function(s)

prostaglandin-D synthase activity
transporter activity
retinoid binding
fatty acid binding
protein binding
small molecule binding