Hs02886971_cn

• Gene Symbol: CAMK2D
• Assay Reference Genome Location: Chr.4:113452738 on build GRCh38
• Cytoband: 4q26

Target Gene Details

• Entrez Gene ID: 817
• Gene Name: calcium/calmodulin dependent protein kinase II delta
• Gene Aliases: CAMKD
• Location: Chr.4:113451032-113761927 on Build GRCh38
• Assay Gene Location: Within Exon 26

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CAMK2D	NM_001221.3	19	4166	NP_001212.2
	NM_001321566.1	20	4208	NP_001308495.1
	NM_001321567.1	20	4216	NP_001308496.1
	NM_001321568.1	20	4145	NP_001308497.1
	NM_001321569.1	21	4268	NP_001308498.1
	NM_001321570.1	20	4172	NP_001308499.1
	NM_001321571.1	21	4268	NP_001308500.1
	NM_001321572.1	20	4172	NP_001308501.1
	NM_001321573.1	21	4241	NP_001308502.1
	NM_001321574.1	19	4163	NP_001308503.1
	NM_001321575.1	19	4112	NP_001308504.1
	NM_001321576.1	18	4067	NP_001308505.1
	NM_001321577.1	19	4109	NP_001308506.1
	NM_001321578.1	18	4039	NP_001308507.1
	NM_001321579.1	20	4216	NP_001308508.1
	NM_001321580.1	20	4226	NP_001308509.1
	NM_001321581.1	20	4213	NP_001308510.1
	NM_001321582.1	19	4103	NP_001308511.1
	NM_001321583.1	19	4156	NP_001308512.1
	NM_001321584.1	19	4109	NP_001308513.1
	NM_001321585.1	20	4206	NP_001308514.1
	NM_001321586.1	20	4169	NP_001308515.1
	NM_001321587.1	20	4145	NP_001308516.1
	NM_001321588.1	20	4205	NP_001308517.1
	NM_001321589.1	19	4156	NP_001308518.1
	NM_001321590.1	19	4112	NP_001308519.1
	NM_001321591.1	20	4189	NP_001308520.1
	NM_172127.2	18	4114	NP_742125.1
	NM_172128.2	18	4070	NP_742126.1
	XM_005263253.3	21	4083	XP_005263310.1
	XM_005263254.3	21	4104	XP_005263311.1
	XM_006714330.2	18	3953	XP_006714393.1
	XM_011532289.1	20	4017	XP_011530591.1
	XM_011532290.1	20	4014	XP_011530592.1
	XM_011532291.1	19	3965	XP_011530593.1
	XM_011532292.2	17	3118	XP_011530594.1
	XM_011532295.1	20	4038	XP_011530597.1
	XM_017008672.1	20	4047	XP_016864161.1
	XM_017008673.1	20	4044	XP_016864162.1
	XM_017008674.1	20	4008	XP_016864163.1
	XM_017008675.1	22	4208	XP_016864164.1
	XM_017008676.1	21	3444	XP_016864165.1
	XM_017008677.1	19	3992	XP_016864166.1
	XM_017008678.1	18	3929	XP_016864167.1
	BX538071.1	1	3519
	BX647363.1	1	3676
	CA416772.1	1	340

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv830038	Chr.4:113289857 - 113470695 on Build GRCh38	Gain	CAMK2D ANK2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
MAPK cascade
regulation of cell growth
response to hypoxia
regulation of the force of heart contraction
regulation of membrane depolarization
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
calcium ion transport
regulation of heart contraction
regulation of G2/M transition of mitotic cell cycle
positive regulation of cardiac muscle hypertrophy
regulation of cell communication by electrical coupling
positive regulation of cardiac muscle cell apoptotic process
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
positive regulation of smooth muscle cell migration
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
cellular potassium ion homeostasis
endoplasmic reticulum calcium ion homeostasis
positive regulation of Rac protein signal transduction
positive regulation of GTPase activity
protein autophosphorylation
positive regulation of smooth muscle cell proliferation
protein oligomerization
relaxation of cardiac muscle
regulation of ryanodine-sensitive calcium-release channel activity
interferon-gamma-mediated signaling pathway
regulation of cellular localization
cell growth involved in cardiac muscle cell development
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
cardiac muscle cell contraction
regulation of heart rate by cardiac conduction
regulation of cardiac muscle cell action potential
regulation of cardiac muscle cell action potential involved in regulation of contraction
regulation of cellular response to heat
regulation of histone deacetylase activity
regulation of cell communication by electrical coupling involved in cardiac conduction
regulation of relaxation of cardiac muscle
negative regulation of sodium ion transmembrane transport
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
negative regulation of sodium ion transmembrane transporter activity

Function(s)

protein serine/threonine kinase activity
calmodulin-dependent protein kinase activity
Ras guanyl-nucleotide exchange factor activity
protein binding
calmodulin binding
ATP binding
sodium channel inhibitor activity
titin binding
protein homodimerization activity
ion channel binding
nitric-oxide synthase binding