Hs02925116_cn

• Gene Symbol: MMP16
• Assay Reference Genome Location: Chr.8:88037212 on build GRCh38
• Cytoband: 8q21.3

Target Gene Details

• Entrez Gene ID: 4325
• Gene Name: matrix metallopeptidase 16
• Gene Aliases: C8orf57, MMP-X2, MT-MMP2, MT-MMP3, MT3-MMP
• Location: Chr.8:88037232-88327488 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MMP16	NM_005941.4			NP_005932.2
	AL832595.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3617938	Chr.8:88025337 - 88043428 on Build GRCh38	Gain	MMP16
esv2759625	Chr.8:87951601 - 88121475 on Build GRCh38	Loss	MMP16

More Information

Additional Information:

For this assay, SNP(s) [rs78061395] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

endochondral ossification
proteolysis
extracellular matrix disassembly
collagen catabolic process
chondrocyte proliferation
positive regulation of catalytic activity
embryonic cranial skeleton morphogenesis
craniofacial suture morphogenesis

Function(s)

metalloendopeptidase activity
calcium ion binding
enzyme activator activity
zinc ion binding