Hs02975554_cn

• Gene Symbol: PDE4C
• Assay Reference Genome Location: Chr.19:18218444 on build GRCh38
• Cytoband: 19p13.11

Target Gene Details

• Entrez Gene ID: 5143
• Gene Name: phosphodiesterase 4C
• Gene Aliases: DPDE1
• Location: Chr.19:18207961-18248200 on Build GRCh38
• Assay Gene Location: Within Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PDE4C	NM_000923.4	11	1359	NP_000914.2
	NM_001098818.2	10	1084	NP_001092288.1
	NM_001098819.2	10	1137	NP_001092289.1
	NR_040546.1	9	1034
	XM_011528056.2	10	1090	XP_011526358.1
	XM_011528058.2	8	666	XP_011526360.1
	XM_017026866.1	11	1368	XP_016882355.1
	AK295050.1	10	1600
	AK300888.1	9	984
	AK300983.1	10	1047
	BC109067.1	6	582	AAI09068.1
	BC109068.2	7	632	AAI09069.1
	U66346.1	11	1359	AAB96875.1
	U66347.1	8	2115	AAB96876.1
	U66348.1	5	540	AAB96877.1
	U66349.1			AAB96878.1
	U88712.1	10	1137	AAC51915.1
	U88713.1	10	1084	AAC51916.1
	Z46632.1	10	1231	CAA86601.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470131	Chr.19:18215412 - 18278325 on Build GRCh38	Loss	LOC729966 KIAA1683 PDE4C
nsv952420	Chr.19:18117791 - 18476990 on Build GRCh38	Deletion	LOC729966 KIAA1683 MIR3188 LSM4 LOC102725254 IFI30 LRRC25 JUND MPV17L2 ISYNA1 GDF15 PDE4C ELL MAST3 MIR3189 SSBP4 RAB3A PGPEP1 PIK3R2
nsv833775	Chr.19:18102951 - 18279264 on Build GRCh38	Loss	MAST3 LOC729966 KIAA1683 RAB3A PIK3R2 LOC102725254 IFI30 MPV17L2 PDE4C

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

cAMP catabolic process
signal transduction
negative regulation of insulin secretion

Function(s)

3',5'-cyclic-AMP phosphodiesterase activity
drug binding
metal ion binding