Hs02995482_cn

• Gene Symbol: TOB2
• Assay Reference Genome Location: Chr.22:41446687 on build GRCh38
• Cytoband: 22q13.2

Target Gene Details

• Entrez Gene ID: 10766
• Gene Name: transducer of ERBB2, 2
• Gene Aliases: APRO5, TOB4, TOBL, TROB2
• Location: Chr.22:41433488-41448230 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TOB2	NM_016272.3	1	337	NP_057356.1
	XM_005261315.2	1	1544	XP_005261372.1
	XM_017028539.1	1	1544	XP_016884028.1
	AB051450.1	1	96
	BC028919.1	1	86	AAH28919.1
	BC038957.1	1	110	AAH38957.1
	BM453650.1	1	337

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv516925	Chr.22:41252498 - 41585953 on Build GRCh38	Loss	ACO2 LOC100996598 MIR6889 CSDC2 ZC3H7B POLR3H LOC105373044 PMM1 TOB2 TEF PHF5A RANGAP1
nsv834207	Chr.22:41282650 - 41463790 on Build GRCh38	Loss	LOC100996598 ZC3H7B TOB2 TEF PHF5A RANGAP1
nsv834208	Chr.22:41363612 - 41554028 on Build GRCh38	Loss	ACO2 LOC100996598 POLR3H LOC105373044 TOB2 TEF PHF5A
nsv459888	Chr.22:41231539 - 41454496 on Build GRCh38	Gain	LOC100996598 MIR6889 ZC3H7B TOB2 TEF CHADL RANGAP1
nsv524585	Chr.22:40993505 - 41794305 on Build GRCh38	Loss	MIR1281 SNORD140 MEI1 ZC3H7B POLR3H XRCC6 TOB2 TEF PHF5A EP300-AS1 DESI1 EP300 RANGAP1 ACO2 LOC100996598 C22orf46 MIR6889 CSDC2 SNU13 LOC105373044 PMM1 L3MBTL2 CHADL

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

female gamete generation
negative regulation of cell proliferation
regulation of gene expression
negative regulation of osteoclast differentiation
positive regulation of ossification

Function(s)

protein binding
vitamin D receptor binding